Louisville Football

Louisville ACC Championship Odds

The Cardinals odds to win the ACC are off the board.

Louisville National Championship Odds

The Cardinals national championship odds are off the board.

Louisville Playoff Odds

The Cardinals odds to make the College Football Playoff are off the board.

Schedule By 365Scores.com
Results By 365Scores.com
Standings By 365Scores.com

Latest Stories

Virginia vs Louisville Prediction, Odds & Best Prop Bets – NCAAF, Week 6

Virginia (4-1) visit L&N Federal Credit Union Stadium to take on Louisville (4-0) on Oct. 4 in Louisville, KY. Kickoff is scheduled for 3:30pm EDT. Louisville is a betting favorite in Week 6, with Read More

BetMGM Betting Oct 02, 2025

Louisville vs Pitt Prediction, Odds & Best Prop Bets – NCAAF, Week 5

Louisville (3-0) visit Acrisure Stadium to take on Pittsburgh (2-1) on Sep. 27 in Pittsburgh, PA. Kickoff is scheduled for 12:00pm EDT. Louisville is a betting favorite in Week 5, with the spread sitt Read More

BetMGM Betting Sep 26, 2025

Bowling Green vs Louisville Prediction, Odds & Best Prop Bets – NCAAF, Week 4

Bowling Green (2-1) visit L&N Federal Credit Union Stadium to take on Louisville (2-0) on Sep. 20 in Louisville, KY. Kickoff is scheduled for 12:00pm EDT. Louisville is a betting favorite in Week Read More

BetMGM Betting Sep 20, 2025

James Madison vs Louisville Prediction, Odds & Best Prop Bets – NCAAF, Week 2

James Madison (1-0) visit L&N Federal Credit Union Stadium to take on Louisville (1-0) on Sep. 5 in Louisville, KY. Kickoff is scheduled for 7:00pm EDT. Louisville is a betting favorite in Week 2, Read More

BetMGM Betting Sep 05, 2025

College Football Predictions & Best Bets for Week 2

Here are BetMGM analyst Chase Kiddy’s best bets and predictions for Week 2. Read More

Chase Kiddy Sep 04, 2025

Who Is the Offensive Coordinator at Louisville?

Who is the offensive coordinator at Louisville? Here’s the answer. Read More

Chase Kiddy Jul 08, 2025

Louisville vs. Boston College: Prediction, Pick, Odds Preview

Here’s a college football betting preview for Louisville vs. Boston College, including the current BetMGM odds and a betting prediction. Read More

Chase Kiddy Oct 23, 2024
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Louisville Football Odds This Week

College football odds are available throughout year, including odds for all ACC teams:

How To Bet On Louisville Football Odds

Spreads, over/under totals, moneylines, and more odds are available for each Louisville football game this season.

  1. Visit the college football betting page.
  2. Find a futures market (e.g., win the ACC Championship) or game market (e.g., Louisville vs. Virginia) to bet on.
  3. Add one or multiple bets to your Bet Slip.
  4. Add a Stake.
  5. Place your bet!

Louisville Football Futures Odds

Will the Cardinals make the College Football Playoff? Will they go over or under their regular-season win total? Will they win the national championship?

For example: If you bet $15 on Louisville (+10000) to make the playoff, the bet would settle when the Cardinals earn a playoff spot.

Louisville Football Spread

What’s the final scoring margin of the game?

For example: If you bet $30 on the Cardinals -13.5 (-115) against Stanford, Louisville must win the game by at least 14 points. 

Alternatively, if you bet $40 on the Cardinals +7.5 (-110) against Miami (FL), Louisville must lose by seven points or less (or win the game).

Louisville Football Moneyline

Will Louisville win the game? 

For example: If you bet $20 on the Cardinals -250 against Pittsburgh, Louisville must win the game (in regulation or overtime).

Louisville Football Over/Under Total

How many total points (by both teams) are scored in the game? 

For example: If you bet $175 on over 59.5 (-105) in their game against NC State, the teams must combine for at least 60. 

Alternatively, if you bet $125 on under 58.5 (-115), the teams must combine for 58 points or fewer.

If the combined point total is the same as the over/under total, the bet is a push.

Louisville Football Parlays

At BetMGM, you may combine multiple bets — for college football or another sport — into parlays.

For example: If you bet $60 on a two-leg parlay with the Louisville football moneyline (-350) vs. Florida State and over 65.5 (-105) in the Duke-Syracuse game, both must hit for the bet to cash.

If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.

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You Better You Bet

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FCS Football Talk

Sam Herder shares his FCS analysis, predictions, thoughts, and ramblings on the FCS Football Talk podcast, presented by HERO Sports and BetMGM.

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The Daily Tip

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BetQL Daily

Daily sports betting analysis with Joe Ostrowski, Ed Egros, and Erin Hawksworth.

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