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The Tigers odds to win the ACC are off the board.
The Tigers national championship odds are off the board.
The Tigers odds to make the College Football Playoff are off the board.
Penn State (6-6) visit Yankee Stadium to take on Clemson (7-5) on Dec. 27 in Bronx, NY. Kickoff is scheduled for 12:00pm EST. Clemson is a betting favorite in the Pinstripe Bowl, with the spread sitti Read More
Bet on Clemson, Miami, SMU, and other ACC football teams to win the 2025 ACC Championship. Read More
Here are the highest and lowest-scoring College Football Playoff games since the CFP was instituted in 2014. Read More
Clemson (4-5) visit L&N Federal Credit Union Stadium to take on Louisville (7-2) on Nov. 14 in Louisville, KY. Kickoff is scheduled for 7:30pm EST. Louisville is a betting favorite in Week 12, wit Read More
Florida State (4-4) visit Memorial Stadium to take on Clemson (3-5) on Nov. 8 in Clemson, SC. Kickoff is scheduled for 7:00pm EST. Clemson is a betting favorite in Week 11, with the spread sitting at Read More
Duke (4-3) visit Memorial Stadium to take on Clemson (3-4) on Nov. 1 in Clemson, SC. Kickoff is scheduled for 12:00pm EDT. Clemson is a betting favorite in Week 10, with the spread sitting at -3.5 (-1 Read More
SMU (4-2) visit Memorial Stadium to take on Clemson (3-3) on Oct. 18 in Clemson, SC. Kickoff is scheduled for 3:30pm EDT. Clemson is a betting favorite in Week 8, with the spread sitting at -9.5 (-110 Read More
Clemson (1-3) visit Kenan Stadium to take on North Carolina (2-2) on Oct. 4 in Chapel Hill, NC. Kickoff is scheduled for 12:00pm EDT. Clemson is a betting favorite in Week 6, with the spread sitting a Read More
Syracuse (2-1) visit Memorial Stadium to take on Clemson (1-2) on Sep. 20 in Clemson, SC. Kickoff is scheduled for 12:00pm EDT. Clemson is a betting favorite in Week 4, with the spread sitting at -17 Read More
College football odds are available throughout year, including odds for all ACC teams:
Spreads, over/under totals, moneylines, and more odds are available for each Clemson football game this season.
Will the Tigers make the College Football Playoff? Will they go over or under their regular-season win total? Will they win the national championship?
For example: If you bet $30 on Clemson (+450) to make the playoff, the bet would settle when the Tigers earn a playoff spot.
What’s the final scoring margin of the matchup?
For example: If you bet $45 on the Tigers -4.5 (-110) against NC State, Clemson must win the game by at least five points.Â
Alternatively, if you bet $95 on the Tigers +2.5 (-115) against SMU, Clemson must lose by two points or less (or win the game).
Will Clemson win the game?Â
For example: If you bet $40 on the Tigers -250 against Syracuse, Clemson must win the game (in regulation or overtime).
How many total points (by both teams) are scored in the game?Â
For example: If you bet $150 on over 58.5 (-105) in their game against Virginia, the teams must combine for at least 59.Â
Alternatively, if you bet $110 on under 58.5 (-115), the teams must combine for 58 points or fewer.
If the combined point total is the same as the over/under total, the bet is a push.
At BetMGM, you may combine multiple bets — for college football or another sport — into parlays.
For example: If you bet $50 on a two-leg parlay with the Clemson football moneyline (-300) vs. Georgia Tech and over 55.5 (-110) in the Louisville-Duke game, both must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
Read the latest betting tips and how-to guides from BetMGM experts.
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