Rams vs 49ers Prediction, Odds & Best Prop Bets – NFL, Week 10

• The Favorite Team are Favorite Spread point favorites vs the Underdog Team
• Total (Over/Under): 49.5 points
• Watch this game on FOX

The Los Angeles Rams (6-2-0) visit Levi's Stadium to take on the San Francisco 49ers (6-3-0) on Nov. 9. Kickoff is scheduled for 4:25pm EST in Santa Clara, CA.

The are betting favorites in this matchup, with the spread sitting at ().

The Rams vs. 49ers Over/Under is 49.5 total points for the game.

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Rams vs. 49ers Odds, Spread, Over/Under

Rams vs. 49ers Prediction

The winning team model predicts the Rams will win this game with 62.4% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Rams vs 49ers Spread Prediction

Based on recent against-the-spread trends, the model predicts the Rams will cover the spread with 50.7% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Rams players this game, looking at profitable historical betting trends:

Best Rams Player Prop Bets Today

• Matthew Stafford has hit the Interceptions Under in 14 of his last 18 games (+9.55 Units / 46% ROI)
• Matthew Stafford has hit the Carries Over in 9 of his last 12 games (+6.60 Units / 44% ROI)
• Puka Nacua has hit the Receiving Yards Over in 12 of his last 17 games (+5.95 Units / 30% ROI)
• Kyren Williams has hit the Receptions Under in 7 of his last 9 away games (+5.85 Units / 52% ROI)
• Tyler Higbee has hit the Receptions Over in 7 of his last 10 games (+4.85 Units / 40% ROI)

And here are some top NFL player prop bets for 49ers players for this matchup, looking at profitable historical betting trends:

Best 49ers Player Prop Best Bets Today

• Christian McCaffrey has hit the Longest Rush Under in 8 of his last 9 games (+6.85 Units / 65% ROI)
• Christian McCaffrey has hit the Rushing Yards Under in 10 of his last 13 games (+6.65 Units / 45% ROI)
• Christian McCaffrey has hit the Receiving Yards Over in 10 of his last 13 games (+6.45 Units / 43% ROI)
• Demarcus Robinson has hit the Receptions Under in his last 6 games at home (+6.15 Units / 74% ROI)
• Christian McCaffrey has hit the Longest Reception Over in 6 of his last 7 games (+4.95 Units / 62% ROI)

Rams Best Bets:

• The Los Angeles Rams have covered the Spread in 17 of their last 22 games (+11.50 Units / 48% ROI)
• The Los Angeles Rams have hit the 2Q Moneyline in 14 of their last 19 games (+8.85 Units / 30% ROI)
• The Los Angeles Rams have covered the 2Q Spread in 14 of their last 19 games (+8.40 Units / 38% ROI)
• The Los Angeles Rams have hit the Moneyline in 15 of their last 22 games (+7.55 Units / 17% ROI)
• The Los Angeles Rams have covered the 2H Spread in 8 of their last 9 away games (+6.92 Units / 67% ROI)

49ers Best Bets:

• The San Francisco 49ers have covered the 1Q Spread in 8 of their last 9 games at home (+7.20 Units / 66% ROI)
• The San Francisco 49ers have hit the 1H Game Total Over in 13 of their last 21 games (+6.15 Units / 25% ROI)
• The San Francisco 49ers have hit the Game Total Over in 13 of their last 21 games (+5.30 Units / 23% ROI)
• The San Francisco 49ers have hit the 1Q Moneyline in 5 of their last 8 games at home (+5.20 Units / 49% ROI)
• The San Francisco 49ers have hit the 3Q Game Total Over in 12 of their last 18 games (+4.85 Units / 22% ROI)

Rams Against the Spread (ATS) Record

Against the spread this NFL season, the Rams are 6-2 (+3.8 Units / 43.18% ROI).

• Rams are 6-2 when betting on the Moneyline for +0.6 Units / 2.21% ROI
• Rams are 3-5 when betting the Over for -2.5 Units / -28.41% ROI
• Rams are 5-3 when betting the Under for +1.7 Units / ROI

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers are 5-4 (+0.6 Units / 6.06% ROI).

• 49ers are 6-3 when betting on the Moneyline for +4.95 Units / 43.81% ROI
• 49ers are 5-3 when betting the Over for +1.7 Units / 17.17% ROI
• 49ers are 3-5 when betting the Under for -2.5 Units / -25.25% ROI

Los Angeles Rams: Keys to the Game vs. the San Francisco 49ers

The Rams have converted late downs on 10 of 92 plays (11%) with 7-10 yards to go this season — 2nd-best in NFL; League Avg: 7%.

The Rams have started 4 drives inside their own 10 yard line in the 1st half since Week 6 — T-most in NFL.

The Rams threw for 4 TDs in Week 9 — T-most in NFL.

The Rams ran successful plays on 74% of pass attempts in the 1st half in Week 9 — 2nd-best in NFL; League Avg: 47%.

San Francisco 49ers: Keys to the Game vs. the Los Angeles Rams

The 49ers have targeted RBs 27% of the time (86 Pass Attempts/323 plays) this season — highest in NFL; League Avg: 17%.

The 49ers have faced a blitz just 9% of the time this season — lowest in NFL; League Avg: 14%.

The 49ers have averaged 10.5 yards per play against open coverage this season — 4th-best in NFL; League Avg: 9.1.

The 49ers have a third down conversion rate of 47% this season — 3rd-best in NFL; League Avg: 39%.

Additional Matchup Notes for Los Angeles Rams vs. San Francisco 49ers

The 49ers have targeted RBs 27% of the time (86 Pass Attempts/323 plays) this season — highest in NFL; League Avg: 17%.

The 49ers have faced a blitz just 9% of the time this season — lowest in NFL; League Avg: 14%.

The 49ers have averaged 10.5 yards per play against open coverage this season — 4th-best in NFL; League Avg: 9.1.

The 49ers have a third down conversion rate of 47% this season — 3rd-best in NFL; League Avg: 39%.

The Rams have converted late downs on 10 of 92 plays (11%) with 7-10 yards to go this season — 2nd-best in NFL; League Avg: 7%.

The Rams have started 4 drives inside their own 10 yard line in the 1st half since Week 6 — T-most in NFL.

The Rams threw for 4 TDs in Week 9 — T-most in NFL.

The Rams ran successful plays on 74% of pass attempts in the 1st half in Week 9 — 2nd-best in NFL; League Avg: 47%.

Los Angeles Rams Offense: Important Stats

The Rams have converted late downs on 10 of 92 plays (11%) with 7-10 yards to go this season — 2nd-best in NFL; League Avg: 7%.

The Rams have started 4 drives inside their own 10 yard line in the 1st half since Week 6 — T-most in NFL.

The Rams threw for 4 TDs in Week 9 — T-most in NFL.

The Rams ran successful plays on 74% of pass attempts in the 1st half in Week 9 — 2nd-best in NFL; League Avg: 47%.

San Francisco 49ers Offense: Important Stats

The 49ers have targeted RBs 27% of the time (86 Pass Attempts/323 plays) this season — highest in NFL; League Avg: 17%.

The 49ers have faced a blitz just 9% of the time this season — lowest in NFL; League Avg: 14%.

The 49ers have averaged 10.5 yards per play against open coverage this season — 4th-best in NFL; League Avg: 9.1.

The 49ers have a third down conversion rate of 47% this season — 3rd-best in NFL; League Avg: 39%.

Los Angeles Rams Defense: Important Stats

The Rams have converted late downs on 10 of 92 plays (11%) with 7-10 yards to go this season — 2nd-best in NFL; League Avg: 7%.

The Rams have started 4 drives inside their own 10 yard line in the 1st half since Week 6 — T-most in NFL.

The Rams threw for 4 TDs in Week 9 — T-most in NFL.

The Rams ran successful plays on 74% of pass attempts in the 1st half in Week 9 — 2nd-best in NFL; League Avg: 47%.

San Francisco 49ers Defense: Important Stats

The 49ers have targeted RBs 27% of the time (86 Pass Attempts/323 plays) this season — highest in NFL; League Avg: 17%.

The 49ers have faced a blitz just 9% of the time this season — lowest in NFL; League Avg: 14%.

The 49ers have averaged 10.5 yards per play against open coverage this season — 4th-best in NFL; League Avg: 9.1.

The 49ers have a third down conversion rate of 47% this season — 3rd-best in NFL; League Avg: 39%.

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More NFL Betting Predictions:

• Anytime & First Touchdown Scorer Predictions
• Receiving Yards Prop Predictions
• Rushing Yards Prop Predictions
• Passing Yards Prop Predictions
• Receptions Made Prop Predictions
• Rushing Attempts Prop Predictions
• Passing Touchdowns Prop Predictions
• QB Interception Prop Predictions
• Field Goals Made Prop Predictions
• NFL Betting Previews: Every Game

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