Lions vs Eagles Prediction, Odds & Best Prop Bets – NFL, Week 11

BetMGM Betting Nov 15, 2025, 9:42 AM

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General view of Lincoln Financial Field during an NFL football game between the San Francisco 49ers and Philadelphia Eagles, Sunday, Sept. 19, 2021, in Philadelphia.

(AP Photo/Rich Schultz)

The Eagles are -2.5 point favorites vs the Lions
Total (Over/Under): 46.5 points
Watch this game on NBC | PEAC | NBCU

The Detroit Lions (6-3-0) visit Lincoln Financial Field to take on the Philadelphia Eagles (7-2-0) on Nov. 16. Kickoff is scheduled for 8:20pm EST in Philadelphia, PA.

The Eagles are betting favorites in this matchup, with the spread sitting at -2.5 (-115).

The Lions vs. Eagles Over/Under is 46.5 total points for the game.

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Lions vs. Eagles Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Lions	+2.5 -105	46.5 -110	120
Eagles	-2.5 -115	46.5 -110	-145

Lions vs. Eagles Prediction

The winning team model predicts the Eagles will win this game with 52.8% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Lions vs Eagles Spread Prediction

Based on recent against-the-spread trends, the model predicts the Eagles will cover the spread with 52.7% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Lions players this game, looking at profitable historical betting trends:

Best Lions Player Prop Bets Today

Jared Goff has hit the Interceptions Under in 7 of his last 8 away games (+5.75 Units / 51% ROI)
Jared Goff has hit the Completions Over in 12 of his last 18 games (+5.10 Units / 24% ROI)
Jahmyr Gibbs has hit the Rushing Yards Over in 12 of his last 18 games (+5.00 Units / 24% ROI)
Jared Goff has hit the TD Passes Over in 12 of his last 18 games (+4.50 Units / 18% ROI)
Jared Goff has hit the Carries Under in 11 of his last 18 games (+4.05 Units / 20% ROI)

And here are some top NFL player prop bets for Eagles players for this matchup, looking at profitable historical betting trends:

Best Eagles Player Prop Best Bets Today

Jalen Hurts has hit the Interceptions Under in 17 of his last 19 games (+13.50 Units / 41% ROI)
Saquon Barkley has hit the Longest Rush Under in 8 of his last 9 games (+6.90 Units / 68% ROI)
Jalen Hurts has hit the TD Passes Over in 7 of his last 11 games at home (+6.65 Units / 60% ROI)
Jalen Hurts has hit the Pass Attempts Under in 13 of his last 19 games (+6.45 Units / 30% ROI)
Jalen Hurts has hit the Carries Under in 13 of his last 19 games (+6.45 Units / 29% ROI)

Lions Best Bets:

The Detroit Lions have covered the 2Q Spread in 13 of their last 18 games (+7.10 Units / 34% ROI)
The Detroit Lions have hit the Moneyline in 7 of their last 9 away games (+6.00 Units / 26% ROI)
The Detroit Lions have covered the 3Q Spread in 7 of their last 8 away games (+5.80 Units / 59% ROI)
The Detroit Lions have hit the 2H Moneyline in 6 of their last 8 away games (+5.50 Units / 41% ROI)
The Detroit Lions have hit the 3Q Moneyline in 6 of their last 8 away games (+5.00 Units / 38% ROI)

Eagles Best Bets:

The Philadelphia Eagles have hit the 3Q Game Total Under in 14 of their last 21 games (+6.30 Units / 27% ROI)
The Philadelphia Eagles have hit the 1Q Game Total Over in 14 of their last 22 games (+6.15 Units / 25% ROI)
The Philadelphia Eagles have hit the 2H Moneyline in 14 of their last 20 games (+4.79 Units / 13% ROI)
The Philadelphia Eagles have hit the 2Q Moneyline in 13 of their last 21 games (+4.65 Units / 12% ROI)
The Philadelphia Eagles have hit the 4Q Game Total Over in 13 of their last 21 games (+3.80 Units / 15% ROI)

Lions Against the Spread (ATS) Record

Against the spread this NFL season, the Lions are 6-3 (+2.7 Units / 27.27% ROI).

Lions are 6-3 when betting on the Moneyline for -0.1 Units / -0.35% ROI
Lions are 5-4 when betting the Over for +0.6 Units / 6.06% ROI
Lions are 4-5 when betting the Under for -1.5 Units / ROI

Eagles Against the Spread (ATS) Record

Against the spread this NFL season, the Eagles are 6-3 (+2.7 Units / 27.27% ROI).

Eagles are 7-2 when betting on the Moneyline for +0.9 Units / 4.16% ROI
Eagles are 5-4 when betting the Over for +0.6 Units / 6.06% ROI
Eagles are 4-5 when betting the Under for -1.5 Units / -15.15% ROI

Detroit Lions: Keys to the Game vs. the Philadelphia Eagles

The Lions have started 17 drives inside opposing territory this season — most in NFL.

The Lions scored on 89% of their drives (8/9) in Week 10 — best in NFL; League Avg: 34%.

The Lions have run successful plays on 61% of pass attempts in the 1st quarter this season — best in NFL; League Avg: 48%.

The Lions have a third down conversion rate of 17% in the 4th quarter this season — worst in NFL; League Avg: 35%.

Philadelphia Eagles: Keys to the Game vs. the Detroit Lions

The Eagles have averaged 12.7 yards per play on contested throws this season — best in NFL; League Avg: 5.6.

The Eagles have averaged 0.75 epa per play on contested throws this season — best in NFL; League Avg: -0.05.

The Eagles have averaged 14.4 yards per play against tight coverage since Week 7 — best in NFL; League Avg: 3.3.

The Eagles have averaged 1.21 epa per play on first read passes since Week 7 — best in NFL; League Avg: 0.21.

Additional Matchup Notes for Detroit Lions vs. Philadelphia Eagles