Giants vs Patriots Prediction, Odds & Best Prop Bets – NFL, Week 13

BetMGM Betting Nov 30, 2025, 9:57 AM

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A general view of Gillette Stadium during the second half an NFL football game between the New England Patriots and the Washington Commanders on Sunday, Nov. 5, 2023, in Foxborough, Mass. (AP Photo/Greg M. Cooper)

(AP Photo/Greg M. Cooper)

The Patriots are -7.5 point favorites vs the Giants
Total (Over/Under): 46.5 points
Watch this game on ESPN | ESPN2 | ESPD

The New York Giants (2-10-0) visit Gillette Stadium to take on the New England Patriots (10-2-0) on Dec. 1. Kickoff is scheduled for 8:15pm EST in Foxborough, MA.

The Patriots are betting favorites in this matchup, with the spread sitting at -7.5 (-105).

The Giants vs. Patriots Over/Under is 46.5 total points for the game.

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Giants vs. Patriots Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Giants	+7.5 -115	46.5 -110	325
Patriots	-7.5 -105	46.5 -110	-425

Giants vs. Patriots Prediction

The winning team model predicts the Patriots will win this game with 77.4% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Giants vs Patriots Spread Prediction

Based on recent against-the-spread trends, the model predicts the Giants will cover the spread with 55.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Giants players this game, looking at profitable historical betting trends:

Best Patriots Player Prop Bets Today

Mack Hollins has hit the Receptions Over in 12 of his last 16 games (+9.48 Units / 49% ROI)
Demario Douglas has hit the Longest Reception Over in his last 8 games (+8.00 Units / 86% ROI)
TreVeyon Henderson has hit the Longest Reception Under in 9 of his last 10 games (+7.90 Units / 70% ROI)
Drake Maye has hit the Passing Yards Over in 12 of his last 16 games (+7.40 Units / 40% ROI)
Mack Hollins has hit the Receiving Yards Over in 12 of his last 17 games (+6.20 Units / 32% ROI)

And here are some top NFL player prop bets for Patriots players for this matchup, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today

Darius Slayton has hit the Receptions Under in 8 of his last 9 away games (+6.75 Units / 49% ROI)
Wan’Dale Robinson has hit the Receptions Over in 8 of his last 10 away games (+5.80 Units / 44% ROI)
Younghoe Koo has hit the Field Goals Over in 6 of his last 7 games (+5.45 Units / 66% ROI)
Jaxson Dart has hit the TD Passes Over in 6 of his last 7 games (+5.05 Units / 40% ROI)
Darius Slayton has hit the Receiving Yards Under in 7 of his last 9 away games (+4.70 Units / 46% ROI)

Patriots Best Bets:

The New England Patriots have hit the 1H Moneyline in 15 of their last 18 games (+16.25 Units / 53% ROI)
The New England Patriots have hit the Moneyline in 13 of their last 20 games (+9.00 Units / 23% ROI)
The New England Patriots have covered the 2Q Spread in 13 of their last 17 games (+8.15 Units / 41% ROI)
The New England Patriots have covered the 1H Spread in 13 of their last 19 games (+7.65 Units / 35% ROI)
The New England Patriots have covered the Spread in 13 of their last 20 games (+5.30 Units / 24% ROI)

Giants Best Bets:

The New York Giants have hit the 1Q Moneyline in 10 of their last 19 games (+8.65 Units / 44% ROI)
The New York Giants have hit the 1H Team Total Over in 14 of their last 20 games (+7.50 Units / 32% ROI)
The New York Giants have hit the 1H Moneyline in 9 of their last 20 games (+6.35 Units / 31% ROI)
The New York Giants have covered the 1Q Spread in 14 of their last 20 games (+6.25 Units / 24% ROI)
The New York Giants have hit the Team Total Over in 14 of their last 21 games (+6.05 Units / 25% ROI)

Giants Against the Spread (ATS) Record

Against the spread this NFL season, the Giants are 7-5 (+1.5 Units / 11.36% ROI).

Giants are 2-10 when betting on the Moneyline for -4.55 Units / -37.92% ROI
Giants are 7-5 when betting the Over for +1.5 Units / 11.36% ROI
Giants are 5-7 when betting the Under for -2.7 Units / ROI

Patriots Against the Spread (ATS) Record

Against the spread this NFL season, the Patriots are 8-4 (+3.6 Units / 27.59% ROI).

Patriots are 10-2 when betting on the Moneyline for +10.45 Units / 35.42% ROI
Patriots are 6-6 when betting the Over for -0.6 Units / -4.55% ROI
Patriots are 6-6 when betting the Under for -0.6 Units / -4.55% ROI

New York Giants: Keys to the Game vs. the New England Patriots

The Giants defense allowed 237 rushing yards in Week 12 — most in NFL.

The Giants defense has allowed successful plays on 54% of plays in the 4th quarter this season — worst in NFL; League Avg: 42%.

Offenses facing the Giants targeted RBs 36% of the time (15 Pass Attempts/42 plays) in Week 12 — highest in NFL; League Avg: 17%.

The Giants defense has allowed successful plays on 60% of rush attempts in the 4th quarter this season — worst in NFL; League Avg: 42%.

New England Patriots: Keys to the Game vs. the New York Giants

The Giants had 10 receptions for 20+ yards in Week 12 — most in NFL.

The Giants have turned the ball over on downs 8 times in the red zone this season — most in NFL.

The Giants started 4 drives inside their own 10 yard line in Week 12 — T-most in NFL.

The Giants have scored 6 TDs on first drive of the game this season — T-2nd-most in NFL.

Additional Matchup Notes for New York Giants vs. New England Patriots