Giants vs Lions Prediction, Odds & Best Prop Bets – NFL, Week 12

BetMGM Betting Nov 19, 2025, 11:52 AM

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General view as the Seattle Seahawks kick a point after against the Detroit Lions during an NFL football game at Ford Field in Detroit, Sunday, Oct. 28, 2018.

(AP Photo/Rick Osentoski)

The Lions are -10.5 point favorites vs the Giants
Total (Over/Under): 50 points
Watch this game on FOX

The New York Giants (2-9-0) visit Ford Field to take on the Detroit Lions (6-4-0) on Nov. 23. Kickoff is scheduled for 1:00pm EST in Detroit, MI.

The Lions are betting favorites in this matchup, with the spread sitting at -10.5 (-110).

The Giants vs. Lions Over/Under is 50 total points for the game.

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Giants vs. Lions Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Giants	+10.5 -110	50 -110	450
Lions	-10.5 -110	50 -110	-625

Giants vs. Lions Prediction

The winning team model predicts the Lions will win this game with 78.6% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Giants vs Lions Spread Prediction

Based on recent against-the-spread trends, the model predicts the Giants will cover the spread with 51.6% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Giants players this game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today

Darius Slayton has hit the Receptions Under in 7 of his last 8 away games (+5.40 Units / 43% ROI)
Jaxson Dart has hit the TD Passes Over in 6 of his last 7 games (+5.05 Units / 40% ROI)
Jameis Winston has hit the Interceptions Over in his last 5 games (+5.00 Units / 49% ROI)
Wan’Dale Robinson has hit the Receptions Over in 12 of his last 18 games (+4.95 Units / 22% ROI)
Younghoe Koo has hit the Field Goals Over in 5 of his last 6 games (+4.35 Units / 60% ROI)

And here are some top NFL player prop bets for Lions players for this matchup, looking at profitable historical betting trends:

Best Lions Player Prop Best Bets Today

Jared Goff has hit the Carries Under in 12 of his last 18 games (+6.05 Units / 28% ROI)
Jahmyr Gibbs has hit the Rushing Yards Over in 12 of his last 18 games (+5.00 Units / 24% ROI)
Amon-Ra St. Brown has hit the Receiving Yards Over in 7 of his last 9 games at home (+4.65 Units / 45% ROI)
David Montgomery has hit the Rushing Yards Under in 10 of his last 15 games (+4.45 Units / 26% ROI)
Sam LaPorta has hit the Receiving Yards Over in 11 of his last 17 games (+3.90 Units / 20% ROI)

Giants Best Bets:

The New York Giants have hit the 1H Team Total Over in 8 of their last 10 away games (+5.90 Units / 48% ROI)
The New York Giants have hit the 1Q Moneyline in 9 of their last 19 games (+5.35 Units / 27% ROI)
The New York Giants have hit the 3Q Game Total Under in 12 of their last 18 games (+4.85 Units / 23% ROI)
The New York Giants have hit the 1H Game Total Over in 13 of their last 20 games (+4.80 Units / 21% ROI)
The New York Giants have hit the Team Total Over in 13 of their last 21 games (+4.05 Units / 17% ROI)

Lions Best Bets:

The Detroit Lions have covered the 3Q Spread in 12 of their last 18 games (+5.35 Units / 25% ROI)
The Detroit Lions have covered the 2Q Spread in 7 of their last 9 games at home (+4.90 Units / 49% ROI)
The Detroit Lions have hit the 2H Moneyline in 11 of their last 18 games (+4.27 Units / 13% ROI)
The Detroit Lions have hit the 4Q Game Total Over in 11 of their last 18 games (+3.45 Units / 18% ROI)
The Detroit Lions have hit the 2Q Moneyline in 7 of their last 9 games at home (+3.20 Units / 18% ROI)

Giants Against the Spread (ATS) Record

Against the spread this NFL season, the Giants are 6-5 (+0.5 Units / 4.13% ROI).

Giants are 2-9 when betting on the Moneyline for -3.55 Units / -32.27% ROI
Giants are 6-5 when betting the Over for +0.5 Units / 4.13% ROI
Giants are 5-6 when betting the Under for -1.6 Units / ROI

Lions Against the Spread (ATS) Record

Against the spread this NFL season, the Lions are 6-4 (+1.6 Units / 14.55% ROI).

Lions are 6-4 when betting on the Moneyline for -1.1 Units / -3.75% ROI
Lions are 5-5 when betting the Over for -0.5 Units / -4.55% ROI
Lions are 5-5 when betting the Under for -0.5 Units / -4.55% ROI

New York Giants: Keys to the Game vs. the Detroit Lions

The Giants have turned the ball over on downs 7 times in the red zone this season — most in NFL.

The Giants have scored 5 TDs on first drive of the game this season — 3rd-most in NFL.

The Giants have averaged just 5.0 yards per play on motion plays this season — 4th-worst in NFL; League Avg: 5.8.

The Giants have run successful plays on 42% of pass attempts on play action passes this season — 3rd-worst in NFL; League Avg: 52%.

Detroit Lions: Keys to the Game vs. the New York Giants

The Lions defense has allowed a third down conversion rate of 30% on 3rd and short this season — best in NFL; League Avg: 59%.

The Lions defense has stuffed 59% (10/17) of rushing attempts on 3rd and short this season — best in NFL; League Avg: 23%.

The Lions defense has allowed first downs on just 30% of plays on 3rd and short this season — best in NFL; League Avg: 59%.

The Lions defense has not allowed a third down conversion on 3rd and short since Week 8 — best in NFL; League Avg: 55%.

Additional Matchup Notes for New York Giants vs. Detroit Lions