Eagles vs. Rams: NFL Week 3 Odds, Prediction

See the latest NFL Week 3 odds, picks and predictions for Eagles vs. Rams on September 21 at Lincoln Financial Field.
  • The Eagles are a 3.5-point home favorite against the Rams.
  • The Eagles have won each of their last 12 home games.
  • My Eagles vs Rams prediction is for the Rams to cover the spread (+3.5, -105).

It’s a rematch of the 2024 divisional round as the Eagles host the Rams. 

Philadelphia sits at 2-0 after an outright win over the Chiefs in Week 2. Now, Jalen Hurts goes for his 18th straight home win against a team with a win percentage north of 51%.

Meanwhile, the Rams won and covered as 5.5-point road favorites against the Titans. The result gives Sean McVay a 2-0 ATS start with Los Angeles now seeking revenge for its January loss in Philly. 

Bet on Eagles vs. Rams and other NFL matchups with up-to-date NFL odds. 

Eagles vs. Rams: NFL Week 3 Odds

Eagles vs. Rams Prediction

Sunday, September 14

Based on Sean McVay’s record as a market underdog and the Rams’ matchup advantage on offense, my Eagles vs Rams prediction is the Rams Spread (+3.5, -105). 

Part of me wants to see if this line gets to +4 or +4.5. However, it’s the Rams or nothing from an ATS standpoint. 

If Philadelphia’s Week 1 result against the Cowboys is any indicator, Los Angeles should feast on offense. 

The Eagles defense features a glaring weakness. Whoever plays opposite Quinyon Mitchell at CB2 presents a liability for the defense. 

Bettors saw that on full display as the Cowboys moved the ball efficiently. For the Eagles defense, I worry about a matchup against a Puka Nacua-Davante Adams tandem. 

As recent as last January, the Rams offense excelled through the air. The Rams passed for 291 yards and outgained Philadelphia 402-350. 

A pair of long touchdowns gave Philly the edge. Jalen Hurts rushed for a 44-yard touchdown to open the game, with Saquon Barkley providing a 65-yard score. 

Through two games, I’ve left generally unimpressed with the Philadelphia offense. Granted, Los Angeles has yet to face a true offensive test. 

That said, McVay has previously excelled as a market underdog. He’s 23-19-2 ATS in such spots, including 4-2 with Mathew Stafford at +4 or higher. 

Accordingly, I like the Rams to cover the spread on Sunday. However, I wouldn’t mind waiting to see if a better number pops later in the week. 

Betting Eagles vs. Rams: NFL Public Betting

Team% of ATS Bets% of ATS Money% of ML Bets% of ML Money
Rams58%76%41%36%
Eagles42%24%59%64%

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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.