Colts vs Jaguars Prediction, Odds & Best Prop Bets – NFL, Week 14

BetMGM Betting Dec 07, 2025, 9:50 AM

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Footballs are viewed on the field before an NFL football game between the Jacksonville Jaguars and the Tennessee Titans, Sunday, Dec. 29, 2024, in Jacksonville, Fla. (AP Photo/Phelan M. Ebenhack)

(AP Photo/Phelan M. Ebenhack)

The Colts are -1.5 point favorites vs the Jaguars
Total (Over/Under): 47.5 points
Watch this game on CBS

The Indianapolis Colts (8-4-0) visit EverBank Stadium to take on the Jacksonville Jaguars (8-4-0) on Dec. 7. Kickoff is scheduled for 1:00pm EST in Jacksonville, FL.

The Colts are betting favorites in this matchup, with the spread sitting at -1.5 (-110).

The Colts vs. Jaguars Over/Under is 47.5 total points for the game.

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Colts vs. Jaguars Odds, Spread, Over/Under

	Spread	Total (O/U)	Moneyline
Colts	-1.5 -110	47.5 -110	-130
Jaguars	+1.5 -110	47.5 -110	110

Colts vs. Jaguars Prediction

The winning team model predicts the Colts will win this game with 65.2% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Colts vs Jaguars Spread Prediction

Based on recent against-the-spread trends, the model predicts the Colts will cover the spread with 61.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Colts players this game, looking at profitable historical betting trends:

Best Colts Player Prop Bets Today

Alec Pierce has hit the Receiving Yards Over in 11 of his last 13 games (+8.75 Units / 58% ROI)
Alec Pierce has hit the Longest Reception Over in 9 of his last 10 games (+7.85 Units / 68% ROI)
Michael Pittman has hit the Receptions Over in his last 7 away games (+7.35 Units / 90% ROI)
Michael Pittman has hit the Longest Reception Under in 7 of his last 9 games (+4.80 Units / 46% ROI)
Daniel Jones has hit the TD Passes Over in 6 of his last 8 games (+4.40 Units / 47% ROI)

And here are some top NFL player prop bets for Jaguars players for this matchup, looking at profitable historical betting trends:

Best Jaguars Player Prop Best Bets Today

Travis Etienne has hit the Longest Rush Under in his last 5 games at home (+5.00 Units / 84% ROI)
Dyami Brown has hit the Longest Reception Under in 6 of his last 7 games (+4.85 Units / 61% ROI)
Travis Etienne has hit the Carries Over in 11 of his last 17 games (+4.35 Units / 23% ROI)
Travis Etienne has hit the Longest Reception Under in 5 of his last 6 games at home (+3.95 Units / 58% ROI)
Trevor Lawrence has hit the Rushing Yards Over in 5 of his last 6 games (+3.85 Units / 55% ROI)

Colts Best Bets:

The Indianapolis Colts have hit the 1H Team Total Over in 13 of their last 19 games (+7.00 Units / 30% ROI)
The Indianapolis Colts have hit the Game Total Over in 12 of their last 19 games (+5.40 Units / 26% ROI)
The Indianapolis Colts have covered the 1Q Spread in 7 of their last 9 away games (+4.60 Units / 39% ROI)
The Indianapolis Colts have hit the 4Q Game Total Over in 10 of their last 16 games (+4.20 Units / 23% ROI)
The Indianapolis Colts have hit the Team Total Over in 12 of their last 19 games (+3.70 Units / 16% ROI)

Jaguars Best Bets:

The Jacksonville Jaguars have hit the 3Q Game Total Under in 12 of their last 17 games (+6.15 Units / 31% ROI)
The Jacksonville Jaguars have hit the Team Total Over in 13 of their last 20 games (+4.10 Units / 17% ROI)
The Jacksonville Jaguars have hit the 3Q Moneyline in 8 of their last 17 games (+3.20 Units / 16% ROI)
The Jacksonville Jaguars have hit the 1Q Moneyline in 7 of their last 18 games (+3.00 Units / 14% ROI)
The Jacksonville Jaguars have covered the 1Q Spread in 12 of their last 20 games (+2.60 Units / 10% ROI)

Colts Against the Spread (ATS) Record

Against the spread this NFL season, the Colts are 7-5 (+1.5 Units / 11.36% ROI).

Colts are 8-4 when betting on the Moneyline for +2.95 Units / 8.85% ROI
Colts are 6-6 when betting the Over for -0.6 Units / -4.55% ROI
Colts are 6-6 when betting the Under for -0.6 Units / ROI

Jaguars Against the Spread (ATS) Record

Against the spread this NFL season, the Jaguars are 7-5 (+1.5 Units / 11.36% ROI).

Jaguars are 8-4 when betting on the Moneyline for +5.15 Units / 32.19% ROI
Jaguars are 6-6 when betting the Over for -0.6 Units / -4.55% ROI
Jaguars are 6-6 when betting the Under for -0.6 Units / -4.55% ROI

Indianapolis Colts: Keys to the Game vs. the Jacksonville Jaguars

The Colts were 7-3 (.700) when allowing less than 50% of third down conversion opportunities last season — 9th-best in NFL; League Avg: .571.

The Colts were winless (0-4) vs top 10 offenses last season — T-worst in NFL; League Avg: .318.

The Colts were winless (0-6) when rushing less than 25 times last season — T-worst in NFL; League Avg: .278.

The Colts were 6-3 (.667) when within 7 points at the two minute warning last season — T-6th-best in NFL; League Avg: .500.

Jacksonville Jaguars: Keys to the Game vs. the Indianapolis Colts

The Jaguars defense allowed a passer rating of 126.0 on 3rd and long (75 Pass Attempts) last season — worst in NFL; League Avg: 83.1.

The Jaguars defense allowed 71 receptions for 20+ yards last season — most in NFL.

The Jaguars defense allowed 403.5 yards from scrimmage per game last season — 2nd-worst in NFL; League Avg: 353.3.

The Jaguars defense allowed 4.8 touchdowns per interception (29 TDs allowed, and 6 INT) last season — 2nd-worst in NFL; League Avg: 2.1.

Additional Matchup Notes for Indianapolis Colts vs. Jacksonville Jaguars