Since the 2005-06 NFL season, 168 teams have been an underdog of at least 14 points in a regular-season or postseason game. The underdog has covered the spread 85 times and pushed five times for an ATS (against the spread) winning percentage of .521.
The underdog has only 13 of those 168 games. The Miami Dolphins are the only team to win twice as an underdog of at least 14 points, while the New Orleans Saints and Pittsburgh Steelers are the only teams to lose twice as favorite at least 14 points.
Here are the biggest point spread upsets in NFL betting of the last 20 years, all of which occurred in the regular season:
| Spread | Date | Matchup | Score |
|---|---|---|---|
| 17.5 | Dec. 29, 2019 | Dolphins (+17.5) at Patriots | 27-24 |
| 17.5 | Dec. 20, 2020 | Jets (+17.5) at Rams | 23-20 |
| 16.5 | Sept. 23, 2018 | Bills (+16.5) at Vikings | 27-6 |
| 16 | Nov. 7, 2021 | Bills at Jaguars (+16) | 9-6 |
| 14.5 | Dec. 6, 2009 | Raiders (+14.5) at Steelers | 27-24 |
| 14.5 | Dec. 21, 2020 | Steelers at Bengals (+14.5) | 27-17 |
| 14 | Oct. 18, 2009 | Eagles at Raiders (+14) | 13-9 |
| 14 | Dec. 20, 2009 | Cardinals at Lions (+14) | 13-9 |
| 14 | Dec. 27, 2009 | Bucs (+14) at Saints | 31-24 |
| 14 | Oct. 15, 2017 | Giants (+14) at Broncos | 20-17 |
| 14 | Oct. 15, 2017 | Dolphins (+14) at Falcons | 23-10 |
| 14 | Nov. 10, 2019 | Falcons (+14) at Saints | 26-9 |
| 14 | Jan. 9, 2022 | Colts at Jaguars (+14) | 26-11 |
Visit the best online sportsbook for point spreads and more NFL odds each week of the season. You can also bet on futures odds, including Super Bowl winner and team win totals.
If you don’t have a BetMGM account, check out updated sportsbook promotions for a potential welcome offer or Refer A Friend bonus.
The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.
