49ers vs Saints Prediction, Odds & Best Prop Bets – NFL, Week 2

• The 49ers are -4.5 point favorites vs the Saints
• Total (Over/Under): 42.5 points
• Watch this game on FOX

The San Francisco 49ers (1-0-0) visit Caesars Superdome to take on the New Orleans Saints (0-1-0) on Sep. 14. Kickoff is scheduled for 1:00pm EDT in New Orleans, LA.

The 49ers are betting favorites in this matchup, with the spread sitting at -4.5 (-110).

The 49ers vs. Saints Over/Under is 42.5 total points for the game.

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49ers vs. Saints Odds, Spread, Over/Under

49ers vs. Saints Prediction

The winning team model predicts the 49ers will win this game with 68.7% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

49ers vs Saints Spread Prediction

Based on recent against-the-spread trends, the model predicts the 49ers will cover the spread with 60.7% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for 49ers players this game, looking at profitable historical betting trends:

Best 49ers Player Prop Bets Today

• Demarcus Robinson has hit the Receptions Under in 15 of his last 17 games (+12.55 Units / 54% ROI)
• Brian Robinson has hit the Receptions Under in 12 of his last 16 games (+7.55 Units / 33% ROI)
• Jauan Jennings has hit the Receptions Over in 11 of his last 15 games (+7.05 Units / 38% ROI)
• Brock Purdy has hit the Carries Over in 10 of his last 13 games (+6.65 Units / 41% ROI)
• Brock Purdy has hit the Rushing Yards Over in 11 of his last 15 games (+6.40 Units / 37% ROI)

And here are some top NFL player prop bets for Saints players for this matchup, looking at profitable historical betting trends:

Best Saints Player Prop Best Bets Today

• Foster Moreau has hit the Receiving Yards Over in 10 of his last 13 games (+6.50 Units / 43% ROI)
• Foster Moreau has hit the Receptions Over in 6 of his last 7 games at home (+5.55 Units / 65% ROI)
• Kevin Austin Jr. has hit the Receptions Under in his last 5 games (+5.40 Units / 82% ROI)
• Juwan Johnson has hit the Receptions Over in 9 of his last 13 games (+4.55 Units / 28% ROI)
• Juwan Johnson has hit the Receiving Yards Over in 9 of his last 13 games (+4.45 Units / 29% ROI)

49ers Best Bets:

• The San Francisco 49ers have hit the 2H Game Total Over in 10 of their last 12 games (+7.75 Units / 59% ROI)
• The San Francisco 49ers have hit the 4Q Game Total Over in 10 of their last 12 games (+7.65 Units / 57% ROI)
• The San Francisco 49ers have covered the 1Q Spread in 13 of their last 19 games (+7.35 Units / 34% ROI)
• The San Francisco 49ers have hit the 1Q Moneyline in 11 of their last 18 games (+5.00 Units / 19% ROI)
• The San Francisco 49ers have hit the 3Q Game Total Over in 6 of their last 7 away games (+4.85 Units / 55% ROI)

Saints Best Bets:

• The New Orleans Saints have hit the 1H Moneyline in 9 of their last 18 games (+4.70 Units / 22% ROI)
• The New Orleans Saints have hit the 4Q Game Total Over in 6 of their last 8 games at home (+3.90 Units / 42% ROI)
• The New Orleans Saints have hit the 2H Game Total Over in 6 of their last 8 games at home (+3.78 Units / 42% ROI)
• The New Orleans Saints have hit the 1H Team Total Under in 11 of their last 18 games (+3.55 Units / 18% ROI)
• The New Orleans Saints have hit the 2Q Game Total Over in 9 of their last 14 games (+3.20 Units / 19% ROI)

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers are 1-0 (+1 Units / 90.91% ROI).

• 49ers are 1-0 when betting on the Moneyline for +1 Units / 74.07% ROI
• 49ers are 0-1 when betting the Over for -1.1 Units / -100% ROI
• 49ers are 1-0 when betting the Under for +1 Units / ROI

Saints Against the Spread (ATS) Record

Against the spread this NFL season, the Saints are 0-1 (-1.1 Units / -100% ROI).

• Saints are 0-1 when betting on the Moneyline for -1 Units / -100% ROI
• Saints are 0-1 when betting the Over for -1.1 Units / -100% ROI
• Saints are 1-0 when betting the Under for +1 Units / 90.91% ROI

San Francisco 49ers: Keys to the Game vs. the New Orleans Saints

New Orleans Saints: Keys to the Game vs. the San Francisco 49ers

Additional Matchup Notes for San Francisco 49ers vs. New Orleans Saints

San Francisco 49ers Offense: Important Stats

New Orleans Saints Offense: Important Stats

San Francisco 49ers Defense: Important Stats

New Orleans Saints Defense: Important Stats

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More NFL Betting Predictions:

• Anytime & First Touchdown Scorer Predictions
• Receiving Yards Prop Predictions
• Rushing Yards Prop Predictions
• Passing Yards Prop Predictions
• Receptions Made Prop Predictions
• Rushing Attempts Prop Predictions
• Passing Touchdowns Prop Predictions
• QB Interception Prop Predictions
• Field Goals Made Prop Predictions
• NFL Betting Previews: Every Game

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