Michigan State vs. Bryant: Prediction, Odds, March Madness

Tom Izzo’s latest tournament campaign begins with a round of 64 clash against Bryant. 

Michigan State, a two-seed in the 2025 NCAA Tournament, finished first in the Big Ten regular season but failed to capture a conference tournament title. 

Bryant earned an automatic bid to the NCAA Tournament as winners of the AEC Conference. Phil Martelli’s side arrives at Friday’s game on a six-game winning streak. 

Bet on Michigan State vs. Bryant and other March Madness matchups with up-to-date college basketball odds. 

Michigan State vs. Bryant Odds, March Madness

• Michigan State Moneyline: -2500
• Bryant Moneyline: +1050
• Game Spread: Michigan State -17.5 (-110), Bryant +17.5 (-110)
• Game Over/Under: 152.5 Points (-110/-110)

Michigan State vs. Bryant Prediction

Based on one historically profitable NCAAB betting system, the Michigan State vs. Bryant prediction for Friday’s game is the Michigan State Spread (-17.5, -110). 

Driving this prediction is Michigan State’s ability to convert from the free-throw line at a high frequency. 

The Spartans shot 78.5% from the free-throw line this season, which triggers a historically profitable system in their favor. 

Since 2006, teams with a free-throw percentage north of 77.2% are 49-16-1 ATS, assuming the team’s spread falls between -20 and +2. 

This system also improves percentage-wise with bigger favorites. 

Sample teams listed between -20 and -7: 8-2-1 ATS, including 4-0-1 ATS when listed at -10 or higher. 

This system has performed exceptionally over the last three years as well. 

Based on the original sample, teams are 23-2 ATS over the last three seasons. At -7 or higher over the last three years: 5-0 ATS. 

As a result, bettors should consider laying the points with Michigan State on Friday. 

Michigan State vs. Bryant: NCAAB Public Betting