Louisville vs Indiana Prediction, Odds & Best Bets Today – NCAAB, Dec. 6

(AP Photo/Charlie Riedel)
  • Louisville is a -4.5 point favorite vs Indiana
  • Total (Over/Under): 161.5 points
  • Louisville / Indiana TV channel: CBS

The Louisville Cardinals visit Gainbridge Fieldhouse to take on the Indiana Hoosiers on Dec. 6. Tip off is scheduled for 2:15pm EST in Indianapolis, IN.

Louisville is the betting favorite in this game, with the spread sitting at -4.5 (-105).

The Louisville vs. Indiana Over/Under is 161.5 total points.

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Louisville vs. Indiana Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Louisville-4.5 -105O 161.5 -105-190
Indiana +4.5 -115U 161.5 -115155

Louisville vs Indiana Prediction for Today:

The winning team model predicts Louisville will win this college basketball game with 68.1% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Louisville vs Indiana Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Louisville will cover the spread with 54.5% confidence for today’s game.


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  • Louisville has hit the Moneyline in 28 of their last 34 games (+18.45 Units / 1% ROI)
  • Louisville has hit the 1H Moneyline in 28 of their last 34 games (+13.65 Units / 1% ROI)
  • Louisville have covered the 1H Spread in 23 of their last 35 games (+11.65 Units / 29% ROI)
  • Louisville have covered the Spread in 21 of their last 35 games (+5.65 Units / 15% ROI)
  • Louisville has hit the Team Total Over in 20 of their last 35 games (+2.64 Units / 7% ROI)
  • Indiana has hit the Moneyline in 20 of their last 32 games (+12.75 Units / 1% ROI)
  • Indiana has hit the 1H Moneyline in 16 of their last 32 games (+5.50 Units / 0% ROI)
  • Indiana has hit the Game Total Under in 19 of their last 32 games (+4.70 Units / 13% ROI)
  • Indiana have covered the Spread in 18 of their last 32 games (+2.55 Units / 7% ROI)

Louisville Basketball Against the Spread Record (ATS)

Louisville has a 5-3 record against the spread this college basketball season (+1.75 Units / 20% ROI).

  • 6-1 when betting on the Moneyline for +4.65 Units / 0.29% ROI
  • 4-4 when betting the Over for -0.45 Units / -5.08% ROI
  • 4-4 when betting the Under for -0.4 Units / -4.57% ROI

Indiana Basketball Against the Spread Record (ATS)

Indiana has a 5-3 record against the spread this college basketball season (+1.7 Units / 19.32% ROI).

  • 7-1 when betting on the Moneyline for +2.4 Units / 0.11% ROI
  • 4-4 when betting the Over for -0.4 Units / -4.55% ROI
  • 4-4 when betting the Under for -0.4 Units / -4.55% ROI

Louisville Offensive Stats & Trends:

Louisville allowed an average of 1.40 points per shot (1,958 points/1,397 shots) last season — 5th highest among Power Conference defenses; League Avg: 1.28

Louisville allowed opponents to shoot 48% (450/927) in the first half last season — highest among ACC Teams; League Avg: 43%

Louisville allowed opponents to shoot 37% from three (266/714) last season — highest among ACC Teams; League Avg: 34%

Louisville allowed an average of 1.35 points per shot (2,463 points/1,827 shots) last season — highest among ACC Teams; League Avg: 1.22

Indiana Offensive Stats & Trends:

Indiana has an assist to turnover ratio of 2.1 (160 assists/ 75 TOs) this season — tied for 3rd best among Division 1 Teams; League Avg: 1.2

Indiana made 5.0 three-pointers per game last season — lowest among Power Conference teams; League Avg: 7.7

Indiana made 5.0 three-pointers per game last season — 8th lowest among Division 1 Teams; League Avg: 7.5

Indiana has made 6.2 three-pointers per game since the start of the 2023-24 season — 2nd lowest among Power Conference teams; League Avg: 7.9

Louisville Defensive Stats & Trends:

Louisville allowed an average of 1.40 points per shot (1,958 points/1,397 shots) last season — 5th highest among Power Conference defenses; League Avg: 1.28

Louisville allowed opponents to shoot 48% (450/927) in the first half last season — highest among ACC Teams; League Avg: 43%

Louisville allowed opponents to shoot 37% from three (266/714) last season — highest among ACC Teams; League Avg: 34%

Louisville allowed an average of 1.35 points per shot (2,463 points/1,827 shots) last season — highest among ACC Teams; League Avg: 1.22

Indiana Defensive Stats & Trends:

Indiana has an assist to turnover ratio of 2.1 (160 assists/ 75 TOs) this season — tied for 3rd best among Division 1 Teams; League Avg: 1.2

Indiana made 5.0 three-pointers per game last season — lowest among Power Conference teams; League Avg: 7.7

Indiana made 5.0 three-pointers per game last season — 8th lowest among Division 1 Teams; League Avg: 7.5

Indiana has made 6.2 three-pointers per game since the start of the 2023-24 season — 2nd lowest among Power Conference teams; League Avg: 7.9


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.