Houston March Madness Odds: Championship, Final Four, Sweet 16

Houston head coach Kelvin Sampson reacts during the first half of an NCAA college basketball game against the Baylor Saturday, March 8, 2025, in Waco, Texas.
(AP Photo/Julio Cortez)
  • Houston has reached the Sweet 16 in five consecutive NCAA Tournaments.
  • Houston is currently fourth in the national championship odds table.

Houston men’s basketball has become a national power under head coach Kelvin Sampson, reaching the second weekend of March Madness in five consecutive tournaments dating back to 2019. 

Once again, Houston is considered one of the top national contenders in BetMGM’s 2025 college basketball futures market. 

I have much more national analysis in my March Madness odds article, which I recommend you read as a helpful guide to betting the NCAA Tournament. 

But for anyone who’s focused on the Cougars specifically, here’s a look at the Houston basketball odds market.  

Houston March Madness Odds

Round ReachedMarch Madness Odds
National Championship+600
Final Four+120
Elite Eight-135
Sweet 16-300
Round of 32[off the board]

Houston National Championship Odds

Houston men’s basketball is +600 to win the 2025 national championship. 

Houston Final Four Odds

Houston men’s basketball is +120 to reach the 2025 Final Four. 

Houston Elite Eight Odds

Houston men’s basketball is -135 to reach the 2025 Final Four. 

Houston Sweet 16 Odds

Houston men’s basketball is -300 to reach the 2025 Final Four. 

Houston NCAA Tournament Odds

Houston is a 28.5-point favorite in its first-round game against SIU-Edwardsville. 

You can check out my breakdown of the full NCAA Tournament schedule right at that link. 

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The content provided in this blog is intended for entertainment purposes only. All views and opinions expressed are the authors and reflect their individual perspectives on sports, betting, and related topics. This content should not be considered professional betting advice or the official views of BetMGM LLC. Please gamble responsibly. If you or someone you know is experiencing issues related to gambling, seek help from a licensed health professional. This blog is not liable for any losses, damages, or consequences resulting from betting activities.

About the Author Read More @chaseakiddy

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.