- South Carolina is a -4.5 point favorite vs. Vanderbilt
- Vanderbilt vs. South Carolina Total (Over/Under): 48.5 points
- TV Channel: SECN
Vanderbilt (2-0) visit Williams-Brice Stadium to take on South Carolina (2-0) on Sep. 13 in Columbia, SC. Kickoff is scheduled for 7:45pm EDT.
South Carolina is a betting favorite in Week 3, with the spread sitting at -4.5 (-110).
The Vanderbilt vs. South Carolina Over/Under is 48.5 total points.
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Vanderbilt vs. South Carolina Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| Vanderbilt | +4.5 -110 | 48.5 -110 | 165 |
| South Carolina | -4.5 -110 | 48.5 -110 | -200 |
Vanderbilt vs South Carolina Prediction:
The winning team model predicts South Carolina will win this game with 63.9% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both Vanderbilt and South Carolina, key player performances this season and recent team trends.
Vanderbilt vs South Carolina Spread Prediction:
Based on recent against-the-spread trends, the model predicts South Carolina will cover the spread with 63.2% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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Vanderbilt Best Bets Today
- Vanderbilt has hit the Moneyline in 6 of their last 12 games (+11.35 Units / 21% ROI)
- Vanderbilt has hit the 1H Moneyline in 5 of their last 10 games (+10.55 Units / 36% ROI)
- Vanderbilt have covered the Spread in 9 of their last 13 games (+4.60 Units / 32% ROI)
- Vanderbilt has hit the 1H Game Total Under in 5 of their last 6 away games (+3.90 Units / 57% ROI)
- Vanderbilt have covered the 1Q Spread in 7 of their last 11 games (+2.30 Units / 18% ROI)
South Carolina Best Bets Today
- South Carolina has hit the 1Q Moneyline in their last 5 games at home (+5.40 Units / 37% ROI)
- South Carolina have covered the Spread in 9 of their last 13 games (+4.60 Units / 32% ROI)
- South Carolina has hit the 1H Moneyline in 4 of their last 5 games at home (+3.55 Units / 14% ROI)
- South Carolina have covered the 1H Spread in 8 of their last 12 games (+3.45 Units / 25% ROI)
- South Carolina have covered the 1Q Spread in 4 of their last 5 games at home (+3.00 Units / 53% ROI)
Vanderbilt Against the Spread (ATS) Record
Vanderbilt is 2-0 against the spread this college football season (+2 Units / 90.91% ROI).
- Vanderbilt is 1-0 when betting on the Moneyline for +1.1 Units / 110% ROI
- Vanderbilt is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
- Vanderbilt is 1-1 when betting the Under for -0.1 Units / -4.55% ROI
South Carolina Against the Spread (ATS) Record
South Carolina iss 1-1 against the spread this college football season (-0.1 Units / -4.55% ROI).
- South Carolina is 1-0 when betting on the Moneyline for +1 Units / 38.46% ROI
- South Carolina is 0-2 when betting the Over for -2.2 Units / -100% ROI
- South Carolina is 2-0 when betting the Under for +2 Units / 90.91% ROI
Vanderbilt: Keys to the Game vs. South Carolina
Vanderbilt was 5-1 (.833) when allowing less than 50% of third down conversion opportunities last season– T-16th-best in FBS; Average: .602
Vanderbilt was 5-1 (.833) when allowing less than 50% of third down conversion opportunities last season– T-10th-best among Power Conference Teams; Average: .645
Vanderbilt is 8-2 (.800) when making 7 or more explosive plays since the 2024 season– T-28th-best in FBS; Average: .646
Vanderbilt was 6-2 (.750) when making 7 or more explosive plays last season– T-34th-best in FBS; Average: .628
South Carolina: Keys to the Game vs. Vanderbilt
South Carolina was undefeated (7-0) when making 5 or more explosive passes in a game last season– T-best among Power Conference Teams; Average: .631
South Carolina is undefeated (7-0) when making 5 or more explosive passes in a game since the 2024 season– T-best among Power Conference Teams; Average: .661
South Carolina was 9-3 (.750) when allowing less than 5 yards per rush last season– T-36th-best in FBS; Average: .632
South Carolina is undefeated (5-0) when not losing a fumble since the 2024 season– T-best among Power Conference Teams; Average: .678
Matchup Notes for Vanderbilt vs. South Carolina
South Carolina’s offense has thrown for 20 or more yards on 15.4% of 39 attempts this season — T-22nd-best among FBS offenses. Vanderbilt’s defense allowed 20+ yards on just 4.3% of attempts this season — 3rd-best among SEC defenses.
South Carolina’s WRs has gained 233 yards on 13 receptions (17.9 YPR) this season — 5th-best among Power 5 WRs. Vanderbilt’s defense has allowed just 8.2 Yards Per Reception this season — 3rd-best among SEC defenses.
South Carolina’s offense has thrown for 20 or more yards on 15.4% of 39 attempts this season — T-22nd-best among FBS offenses. Vanderbilt’s defense allowed 20+ yards on just 4.3% of attempts this season — T-14th-best among FBS defenses.
Vanderbilt’s offense has thrown for 20 or more yards on 18.8% of 48 attempts this season — 8th-best among FBS offenses. South Carolina’s defense allowed 20+ yards on 14.3% of attempts this season — 16th-worst among FBS defenses.
Vanderbilt has gained 477 yards on 32 receptions (14.9 YPR) this season — 13th-best among FBS skill players. South Carolina’s defense has allowed 13.0 Yards Per Reception this season — T-23rd-worst among FBS defenses.
Vanderbilt’s offense has thrown for 20 or more yards on 18.8% of 48 attempts this season — 8th-best among FBS offenses. South Carolina’s defense allowed 20+ yards on 14.3% of attempts this season — 2nd-worst among SEC defenses.
Vanderbilt Offensive Stats & Trends
Vanderbilt’s offense has thrown for 20 or more yards on 18.8% of 48 attempts this season — 8th-best among FBS offenses. South Carolina’s defense allowed 20+ yards on 14.3% of attempts this season — 16th-worst among FBS defenses.
Vanderbilt WRs were targeted 11.6 times per game (151/13) last season– lowest among SEC Teams; Average: 19.7
Vanderbilt WRs averaged just 6.6 receptions per game (86/13) last season– worst among SEC Teams; Average: 12.0
Vanderbilt has gained 477 yards on 32 receptions (14.9 YPR) this season — 13th-best among FBS skill players. South Carolina’s defense has allowed 13.0 Yards Per Reception this season — T-23rd-worst among FBS defenses.
Vanderbilt’s offense has thrown for 20 or more yards on 18.8% of 48 attempts this season — 8th-best among FBS offenses. South Carolina’s defense allowed 20+ yards on 14.3% of attempts this season — 2nd-worst among SEC defenses.
South Carolina Offensive Stats & Trends
South Carolina WRs have averaged 30.0 yards per reception (120 yards/4 catches) this season– 2nd-best among FBS Teams; Average: 12.5
South Carolina have been sacked on 21% of pass attempts (4/19) this season– worst among SEC Offenses; Average: 4%
South Carolina WRs have averaged 30.0 yards per reception (120 yards/4 catches) this season– best among SEC Teams; Average: 13.4
South Carolina’s offense has thrown for 20 or more yards on 15.4% of 39 attempts this season — T-22nd-best among FBS offenses. Vanderbilt’s defense allowed 20+ yards on just 4.3% of attempts this season — 3rd-best among SEC defenses.
South Carolina WRs have averaged 30.0 yards per reception (120 yards/4 catches) this season– best among Power Conference Teams; Average: 13.2
Vanderbilt Defensive Stats & Trends
Vanderbilt has allowed passes of 20+ yards on 10 of 60 attempts (17%) on 3rd and long since the 2024 season– worst in the SEC; Average: 9%
Vanderbilt has sacked opposing QBs on 16% of pass attempts (3/19) this season– best in the SEC; Average: 6%
Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– 2nd-worst among Power Conference Teams; Average: 9%
Vanderbilt allowed passes of 20+ yards on 10 of 52 attempts (19%) on 3rd and long last season– worst in the SEC; Average: 9%
Vanderbilt has allowed opponents to catch 292 of 434 passes (67% Reception Pct) since the 2024 season– 2nd-worst in the SEC; Average: 61%
South Carolina Defensive Stats & Trends
South Carolina has averaged 2.00 interceptions per game (2/1) this season– best in the SEC; Average: 0.56
South Carolina allowed a Completion Pct of just 31% (9 completions/29 attempts) in the Red Zone last season– 2nd-best among Power Conference Teams; Average: 53%
South Carolina allowed a Completion Pct of just 31% (9 completions/29 attempts) in the Red Zone last season– 2nd-best in FBS; Average: 54%
South Carolina’s opponents attempted two-point conversions on 24% of PATs last season– 2nd-highest in FBS; Average: 8%
South Carolina’s opponents has attempted two-point conversions on 23% of PATs since the 2024 season– 2nd-highest in FBS; Average: 8%
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