- Clemson is a -17 point favorite vs. Syracuse
- Syracuse vs. Clemson Total (Over/Under): 55.5 points
- TV Channel: ESPN
Syracuse (2-1) visit Memorial Stadium to take on Clemson (1-2) on Sep. 20 in Clemson, SC. Kickoff is scheduled for 12:00pm EDT.
Clemson is a betting favorite in Week 4, with the spread sitting at -17 (-110).
The Syracuse vs. Clemson Over/Under is 55.5 total points.
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Syracuse vs. Clemson Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| Syracuse | +17 -110 | 55.5 -110 | 575 |
| Clemson | -17 -110 | 55.5 -110 | -900 |
Syracuse vs Clemson Prediction:
The winning team model predicts Clemson will win this game with 80.8% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both Syracuse and Clemson, key player performances this season and recent team trends.
Syracuse vs Clemson Spread Prediction:
Based on recent against-the-spread trends, the model predicts Clemson will cover the spread with 65.0% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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Syracuse Best Bets Today
- Syracuse has hit the Moneyline in 8 of their last 12 games (+6.80 Units / 24% ROI)
- Syracuse has hit the 1H Game Total Over in 5 of their last 7 away games (+3.85 Units / 47% ROI)
- Syracuse has hit the Game Total Over in 8 of their last 14 games (+2.50 Units / 16% ROI)
- Syracuse has hit the 1H Moneyline in 3 of their last 5 away games (+2.40 Units / 20% ROI)
- Syracuse have covered the 1H Spread in 4 of their last 7 away games (+0.60 Units / 8% ROI)
Clemson Best Bets Today
- Clemson has hit the 1H Game Total Under in 6 of their last 7 games at home (+4.90 Units / 62% ROI)
- Clemson has hit the 1Q Game Total Under in 6 of their last 7 games at home (+4.65 Units / 58% ROI)
- Clemson has hit the Game Total Under in 9 of their last 15 games (+3.50 Units / 21% ROI)
- Clemson have covered the 1Q Spread in 4 of their last 7 games at home (+1.00 Units / 14% ROI)
Syracuse Against the Spread (ATS) Record
Syracuse is 1-1 against the spread this college football season (-0.1 Units / -3.03% ROI).
- Syracuse is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
- Syracuse is 2-1 when betting the Over for +0.9 Units / 27.27% ROI
- Syracuse is 1-2 when betting the Under for -1.2 Units / -36.36% ROI
Clemson Against the Spread (ATS) Record
Clemson iss 0-3 against the spread this college football season (-3.25 Units / -100% ROI).
- Clemson is 0-2 when betting on the Moneyline for -3.45 Units / -100% ROI
- Clemson is 0-3 when betting the Over for -3.3 Units / -100% ROI
- Clemson is 3-0 when betting the Under for +3 Units / 90.91% ROI
Syracuse: Keys to the Game vs. Clemson
Syracuse was 8-1 (.889) when rushing at least 4 yards in a play 10 or more times last season– 6th-best among Power Conference Teams; Average: .618
Syracuse was 6-3 (.667) when in a one score game last season– T-12th-best among Power Conference Teams; Average: .514
Syracuse is 8-1 (.889) when rushing for more than 100 yards since the 2024 season– 10th-best among Power Conference Teams; Average: .706
Syracuse is 9-2 (.818) when committing less than 60 yards in penalties since the 2024 season– T-13th-best in FBS; Average: .530
Clemson: Keys to the Game vs. Syracuse
Clemson was undefeated (7-0) when allowing less than 5 yards per rush last season– T-best among Power Conference Teams; Average: .647
Clemson was 9-3 (.750) when rushing at least 4 yards in a play 10 or more times last season– T-32nd-best in FBS; Average: .575
Clemson was 10-2 (.833) when making 5 or more explosive passes in a game last season– T-9th-best among Power Conference Teams; Average: .631
Clemson was undefeated (7-0) when allowing less than 5 yards per rush last season– T-best in FBS; Average: .632
Matchup Notes for Syracuse vs. Clemson
Clemson has 377 receptions in 17 games (22.2 per game) since the 2024 season — 26th-best among FBS skill players. Syracuse’s defense has allowed 21.1 receptions per game since the 2024 season — 5th-worst among ACC defenses.
Clemson’s offense has thrown for 4,532 passing yards in 17 games (266.6 YPG) since the 2024 season — T-24th-best among FBS offenses. Syracuse’s defense has allowed 236.1 passing yards per game since the 2024 season — 33rd-worst among FBS defenses.
Clemson’s WRs has 252 receptions in 17 games (14.8 per game) since the 2024 season — T-27th-best among FBS WRs. Syracuse’s defense has allowed 21.1 receptions per game since the 2024 season — T-14th-worst among FBS defenses.
Syracuse’s offense has thrown for 20 or more yards on 17.7% of 130 attempts this season — 8th-best among FBS offenses. Clemson’s defense allowed 20+ yards on just 6.1% of attempts this season — T-24th-best among FBS defenses.
Syracuse’s offense has thrown for 20 or more yards on 12.9% of 726 attempts since the 2024 season — T-15th-best among FBS offenses. Clemson’s defense allowed 20+ yards on just 8.7% of attempts since the 2024 season — T-4th-best among ACC defenses.
Syracuse’s offense has thrown for 5,948 passing yards in 16 games (371.8 YPG) since the 2024 season — best among FBS offenses. Clemson’s defense has allowed just 215.8 passing yards per game since the 2024 season — T-4th-best among ACC defenses.
Syracuse Offensive Stats & Trends
Syracuse’s offense has thrown for 20 or more yards on 17.7% of 130 attempts this season — 8th-best among FBS offenses. Clemson’s defense allowed 20+ yards on just 6.1% of attempts this season — T-24th-best among FBS defenses.
Syracuse WRs have 6 receptions for 20 or more yards in the 4th quarter this season– most among FBS Teams
Syracuse threw for 6 TDs last week– 3rd-most among FBS Offenses
Syracuse WRs had 10 receptions for 20 or more yards last week– most among Power Conference Teams
Syracuse WRs had 10 receptions for 20 or more yards last week– most among FBS Teams
Clemson Offensive Stats & Trends
Clemson RBs averaged 8.9 yards from scrimmage per touch (277 yards / 31 touches) on 3rd and short last season– best among FBS Teams; Average: 4.4
Clemson has 377 receptions in 17 games (22.2 per game) since the 2024 season — 26th-best among FBS skill players. Syracuse’s defense has allowed 21.1 receptions per game since the 2024 season — 5th-worst among ACC defenses.
Clemson’s offense has thrown for 4,532 passing yards in 17 games (266.6 YPG) since the 2024 season — T-24th-best among FBS offenses. Syracuse’s defense has allowed 236.1 passing yards per game since the 2024 season — 33rd-worst among FBS defenses.
Clemson’s WRs has 252 receptions in 17 games (14.8 per game) since the 2024 season — T-27th-best among FBS WRs. Syracuse’s defense has allowed 21.1 receptions per game since the 2024 season — T-14th-worst among FBS defenses.
Clemson have thrown for 13 TDs in the 3rd quarter since the 2024 season– most among FBS Offenses
Syracuse Defensive Stats & Trends
Syracuse allowed a Completion Pct of just 29% (8 completions/28 attempts) on third and 10+ yards to go last season– best among Power Conference Teams; Average: 55%
Syracuse had no interceptions and 15 TD passes allowed in the Red Zone last season– T-worst in FBS; Average: 9.4
Syracuse has allowed 202.0 yards from scrimmage per game to RBs this season– 2nd-worst among Power Conference Teams; Average: 111.7
Syracuse has averaged a sack every 41.7 pass attempts (125 Pass Attempts/3 Sacks) this season– 4th-worst among Power Conference Teams; Average: 12.7
Syracuse has not forced a fumble (102 carries) this season– T-worst in FBS; Average: 51.5
Clemson Defensive Stats & Trends
Clemson has allowed 6 TD passes in close and late situations since the 2024 season– T-most among Power Conference Teams
Clemson allowed opponents to rush for 20+ yards on 30 of their 477 carries (6%) last season– worst among Power Conference Teams; Average: 3%
Clemson has allowed 11 TDs in close and late situations since the 2024 season– T-most among Power Conference Teams
Clemson has allowed a Completion Pct of just 29% (5 completions/17 attempts) on 3rd and short since the 2024 season– 2nd-best among Power Conference Teams; Average: 61%
Clemson has allowed a Completion Pct of just 29% (5 completions/17 attempts) on 3rd and short since the 2024 season– 2nd-best in FBS; Average: 62%
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