- Missouri is a -10.5 point favorite vs. South Carolina
- South Carolina vs. Missouri Total (Over/Under): 47.5 points
- TV Channel: ESPN
South Carolina (2-1) visit Memorial Stadium/Faurot Field to take on Missouri (3-0) on Sep. 20 in Columbia, MO. Kickoff is scheduled for 7:00pm EDT.
Missouri is a betting favorite in Week 4, with the spread sitting at -10.5 (-110).
The South Carolina vs. Missouri Over/Under is 47.5 total points.
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South Carolina vs. Missouri Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| South Carolina | +10.5 -110 | 47.5 -105 | 275 |
| Missouri | -10.5 -110 | 47.5 -115 | -350 |
South Carolina vs Missouri Prediction:
The winning team model predicts Missouri will win this game with 62.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both South Carolina and Missouri, key player performances this season and recent team trends.
South Carolina vs Missouri Spread Prediction:
Based on recent against-the-spread trends, the model predicts South Carolina will cover the spread with 58.2% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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South Carolina Best Bets Today
- South Carolina have covered the Spread in 4 of their last 5 away games (+2.90 Units / 53% ROI)
- South Carolina have covered the 1H Spread in 4 of their last 5 away games (+2.85 Units / 50% ROI)
- South Carolina has hit the 1H Game Total Under in 4 of their last 5 away games (+2.80 Units / 49% ROI)
- South Carolina has hit the 1Q Game Total Under in 3 of their last 5 away games (+1.70 Units / 29% ROI)
- South Carolina has hit the Game Total Under in 3 of their last 5 away games (+0.80 Units / 15% ROI)
Missouri Best Bets Today
- Missouri has hit the Moneyline in their last 7 games at home (+7.35 Units / 13% ROI)
- Missouri have covered the Spread in 10 of their last 13 games (+6.60 Units / 46% ROI)
- Missouri has hit the Game Total Over in 9 of their last 13 games (+4.60 Units / 32% ROI)
- Missouri have covered the 1Q Spread in 8 of their last 12 games (+3.54 Units / 25% ROI)
- Missouri has hit the 1Q Game Total Over in 7 of their last 12 games (+1.83 Units / 14% ROI)
South Carolina Against the Spread (ATS) Record
South Carolina is 1-2 against the spread this college football season (-1.2 Units / -36.36% ROI).
- South Carolina is 1-1 when betting on the Moneyline for -0.55 Units / -13.25% ROI
- South Carolina is 0-3 when betting the Over for -3.3 Units / -100% ROI
- South Carolina is 3-0 when betting the Under for +3 Units / 90.91% ROI
Missouri Against the Spread (ATS) Record
Missouri iss 3-0 against the spread this college football season (+3 Units / 92.31% ROI).
- Missouri is 2-0 when betting on the Moneyline for +2 Units / 4.76% ROI
- Missouri is 3-0 when betting the Over for +3 Units / 90.91% ROI
- Missouri is 0-3 when betting the Under for -3.3 Units / -100% ROI
South Carolina: Keys to the Game vs. Missouri
South Carolina was undefeated (7-0) when making 5 or more explosive passes in a game last season– T-best among Power Conference Teams; Average: .631
South Carolina is undefeated (5-0) when not losing a fumble since the 2024 season– T-best among Power Conference Teams; Average: .684
South Carolina was 8-3 (.727) when allowing less than 50% of third down conversion opportunities last season– T-38th-best in FBS; Average: .602
South Carolina was 9-3 (.750) when converting 55% or more of its red zone chances into touchdowns last season– T-31st-best in FBS; Average: .624
Missouri: Keys to the Game vs. South Carolina
Missouri State was winless (0-1) when the opposing team converts 55% or more of its red zone chances into touchdowns last season– T-worst in FBS; Average: .418
Missouri State was winless (0-1) when allowing 10 or more rushes of four or more yards last season– T-worst in FBS; Average: .479
Missouri State was winless (0-1) when allowing 200 or more passing yards last season– T-worst among Non-Power Conference Teams; Average: .462
Missouri State was winless (0-1) when allowing 100 or more rushing yards last season– T-worst among Non-Power Conference Teams; Average: .390
Matchup Notes for South Carolina vs. Missouri
There are no matchup notes available for this game
South Carolina’s WRs has gained 411 yards on 28 receptions (14.7 YPR) this season — T-33rd-best among FBS WRs. Missouri’s defense has allowed just 9.1 Yards Per Reception this season — T-4th-best among SEC defenses.
South Carolina’s QBs has thrown for 431 passing yards in 3 games (just 143.7 YPG) this season — T-14th-worst among FBS teams. Missouri’s defense has allowed just 100.0 passing yards per game this season — 5th-best among P5 defenses.
South Carolina’s QBs has thrown for 431 passing yards in 3 games (just 143.7 YPG) this season — T-14th-worst among FBS teams. Missouri’s defense has allowed just 100.0 passing yards per game this season — 2nd-best among SEC defenses.
South Carolina Offensive Stats & Trends
South Carolina TEs averaged 21.5 yards per reception (215 yards/10 catches) in the 4th quarter last season– 2nd-best among Power Conference Teams; Average: 11.3
South Carolina’s WRs has gained 411 yards on 28 receptions (14.7 YPR) this season — T-33rd-best among FBS WRs. Missouri’s defense has allowed just 9.1 Yards Per Reception this season — T-4th-best among SEC defenses.
South Carolina’s QBs has thrown for 431 passing yards in 3 games (just 143.7 YPG) this season — T-14th-worst among FBS teams. Missouri’s defense has allowed just 100.0 passing yards per game this season — 5th-best among P5 defenses.
South Carolina’s QBs has thrown for 431 passing yards in 3 games (just 143.7 YPG) this season — T-14th-worst among FBS teams. Missouri’s defense has allowed just 100.0 passing yards per game this season — 2nd-best among SEC defenses.
South Carolina TEs have averaged 21.5 yards per reception (215 yards/10 catches) in the 4th quarter since the 2024 season– best among Power Conference Teams; Average: 11.3
Missouri Offensive Stats & Trends
Missouri State TEs averaged 27.7 yards per reception (83 yards/3 catches) last season– best among FBS Teams; Average: 11.1
Missouri State RBs averaged -1.0 yards from scrimmage per touch (-3 yards / 3 touches) on 3rd down last season– worst among FBS Teams; Average: 5.6
Missouri State RBs averaged 3.2 yards from scrimmage per touch (70 yards / 22 touches) last season– worst among FBS Teams; Average: 5.4
Missouri State Skill Players averaged just -2.0 yards per reception (-4 yards/2 catches) on 3rd and long last season– worst among FBS Teams; Average: 12.9
Missouri State WRs had no receptions on 2 targets on 3rd and long last season– worst among FBS Teams; Average: 54%
South Carolina Defensive Stats & Trends
South Carolina’s opponents attempted two-point conversions on 24% of PATs last season– 2nd-highest in FBS; Average: 8%
South Carolina’s opponents attempted two-point conversions on 24% of PATs last season– 2nd-highest among Power Conference Teams; Average: 8%
South Carolina allowed a Completion Pct of just 31% (9 completions/29 attempts) in the Red Zone last season– 2nd-best among Power Conference Teams; Average: 53%
South Carolina opponents averaged 39.6 Passing Attempts per TD (396 Pass Attempts/10 Passing TDs) last season– 4th-best in FBS; Average: 20.6
South Carolina allowed a Completion Pct of just 31% (9 completions/29 attempts) in the Red Zone last season– 2nd-best in FBS; Average: 54%
Missouri Defensive Stats & Trends
Missouri State allowed a Completion Pct of 100% (4 completions/4 attempts) on 3rd and long last season– worst in FBS; Average: 55%
Missouri State allowed a Completion Pct of 100% (4 completions/4 attempts) on 3rd and long last season– worst among Non-Power Conference Teams; Average: 55%
Missouri State allowed opponents to catch 4 of 4 passes (100% Reception Pct) on 3rd and long last season– worst in FBS; Average: 55%
Missouri State tackled opponents for a loss on 2 of 6 rushing attempts (33% TFL%) in the Red Zone last season– best among Non-Power Conference Teams; Average: 14%.
Missouri State has allowed a Completion Pct of 85% (11 completions/13 attempts) on 3rd and long since the 2024 season– worst in FBS; Average: 54%
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