Ohio State vs. Indiana: Odds for Big Ten Championship Game

Ohio State defensive tackle Tywone Malone celebrates after the team's win against Michigan in an NCAA college football game, Saturday, Nov. 29, 2025, in Ann Arbor, Mich.
(AP Photo/Ryan Sun)

It’s the game college football fans have been waiting for.

On Saturday night, No. 1 Ohio State will play No. 2 Indiana in a battle for the Big Ten crown and the No. 1 seed in the playoff.

There’s a good chance they could play again in January, with even more on the line. 

Ohio State vs. Indiana Odds

  • Point Spread: Ohio State -5.5
  • Moneyline: Ohio State -220  |  Indiana +180
  • Over/Under: 48.5

Ohio State vs. Indiana

Indiana has the Heisman Trophy favorite playing quarterback in Fernando Mendoza. The Hoosiers can also make a case for a coaching advantage, since Curt Cignetti is arguably the best college football coach in America right now.

But Ohio State has the personnel edge, with loads of future NFL players lining the two-deep and a winning streak that’s now stretching beyond a calendar year. 

Perhaps those who remain from last year’s team feel they have some unfinished business this weekend, since they were boxed out of the 2024 Big Ten Championship Game after their loss to Michigan.

Either way, reigning champ Ohio State is a rightful favorite in this playoff preview.

Big Ten Championship Game History

YearWinnerLoserScore
2024OregonPenn State45-37
2023MichiganIowa26-0
2022MichiganPurdue43-22
2021MichiganIowa42-3
2020Ohio StateNorthwestern22-10
2019Ohio StateWisconsin34-21
2018Ohio StateNorthwestern45-24
2017Ohio StateWisconsin27-21
2016Penn StateWisconsin38-31
2015Michigan StateIowa16-13
2014Ohio StateWisconsin59-0
2013Michigan StateOhio State34-24
2012WisconsinNebraska70-31
2011WisconsinMichigan State42-39

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About the Author Read More @chaseakiddy

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.

Chase Kiddy is a writer for BetMGM and co-host of The Lion's Edge, an NFL and college football podcast available on Spotify, Apple Podcasts, and everywhere else. He has also written for a number of print and online outlets, including the Richmond Times-Dispatch, Washington Post, Daily News-Record, and HERO Sports. His first novel, Cave Paintings, is in development.