Northwestern vs Illinois Prediction, Odds & Best Prop Bets – NCAAF, Week 14

BetMGM Betting Nov 28, 2025, 10:29 AM

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Illinois head coach Bret Bielema watches from the sideline during the second half of an NCAA college football game against Iowa, Saturday, Nov. 18, 2023, in Iowa City, Iowa. Iowa won 15-13. (AP Photo/Charlie Neibergall)

(AP Photo/Charlie Neibergall)

Illinois is a -7 point favorite vs. Northwestern
Northwestern vs. Illinois Total (Over/Under): 47.5 points
TV Channel: FOX

Northwestern (6-5) visit Gies Memorial Stadium (Champaign, IL) to take on Illinois (7-4) on Nov. 29 in Champaign, IL. Kickoff is scheduled for 7:30pm EST.

Illinois is a betting favorite in Week 14, with the spread sitting at -7 (-110).

The Northwestern vs. Illinois Over/Under is 47.5 total points.

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Northwestern vs. Illinois Odds, Spread, Over/Under:

	Spread	Total (O/U)	Moneyline
Northwestern	+7 -110	47.5 -115	220
Illinois	-7 -110	47.5 -105	-275

Northwestern vs Illinois Prediction:

The winning team model predicts Northwesten will win this game with 52.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Northwestern and Illinois, key player performances this season and recent team trends.

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Northwestern Best Bets Today

Northwestern has hit the Moneyline in 6 of their last 12 games (+7.50 Units / 11% ROI)
Northwestern has hit the 1Q Moneyline in 6 of their last 12 games (+5.90 Units / 21% ROI)
Northwestern have covered the 1H Spread in 9 of their last 12 games (+5.40 Units / 38% ROI)
Northwestern have covered the 1Q Spread in 8 of their last 12 games (+4.06 Units / 32% ROI)
Northwestern has hit the Team Total Over in 7 of their last 10 games (+3.50 Units / 30% ROI)

Illinois Best Bets Today

Illinois has hit the 1H Game Total Under in their last 7 games at home (+7.00 Units / 88% ROI)
Illinois has hit the Moneyline in 5 of their last 6 games at home (+6.85 Units / 11% ROI)
Illinois has hit the 1H Moneyline in 6 of their last 7 games at home (+6.55 Units / 12% ROI)
Illinois has hit the Team Total Under in their last 5 games (+5.00 Units / 87% ROI)
Illinois have covered the Spread in 6 of their last 7 games at home (+4.90 Units / 64% ROI)

Northwestern Against the Spread (ATS) Record

Northwestern is 6-4 against the spread this college football season (+1.6 Units / 13.22% ROI).

Northwestern is 6-5 when betting on the Moneyline for +8.5 Units / 12.85% ROI
Northwestern is 6-5 when betting the Over for +0.5 Units / 4.13% ROI
Northwestern is 5-6 when betting the Under for -1.6 Units / -13.22% ROI

Illinois Against the Spread (ATS) Record

Illinois iss 7-4 against the spread this college football season (+2.6 Units / 21.67% ROI).

Illinois is 6-4 when betting on the Moneyline for +0.65 Units / 0.95% ROI
Illinois is 5-6 when betting the Over for -1.6 Units / -13.22% ROI
Illinois is 6-5 when betting the Under for +0.5 Units / 4.13% ROI

Northwestern: Keys to the Game vs. Illinois

Illinois TEs averaged 18.0 yards per reception (36 yards/2 catches) in the 4th quarter last season– best among Big Ten Teams; Average: 10.1

Illinois’s RBs has averaged 9.6 yards after the catch this season — T-25th-best among FBS RBs. Northwestern’s defense has allowed 11.4 RAC this season — T-3rd-worst among Big Ten defenses.

Illinois RBs averaged 8.2 yards from scrimmage per touch (172 yards / 21 touches) on 3rd and short last season– T-4th-best among FBS Teams; Average: 4.4

Illinois’s WRs has averaged 13.6 yards after the catch this season — T-4th-best among Big Ten WRs. Northwestern’s defense has allowed 11.4 RAC this season — T-3rd-worst among Big Ten defenses.

Illinois Skill Players averaged 17.8 yards per reception (551 yards/31 catches) on 3rd and long last season– best among Big Ten Teams; Average: 12.7

Illinois: Keys to the Game vs. Northwestern

Northwestern WRs averaged a touchdown every 32.0 receptions (128 Rec/4 TDs) last season– worst Receptions Per TD among Power Conference Teams; Average: 10.9

Northwestern WRs averaged a touchdown every 32.0 receptions (128 Rec/4 TDs) last season– worst Receptions Per TD among Big Ten Teams; Average: 10.7

Northwestern Skill Players averaged a touchdown every 30.0 receptions (210 Rec/7 TDs) last season– 2nd-worst Receptions Per TD among FBS Teams; Average: 11.7

Northwestern Skill Players averaged a touchdown every 30.0 receptions (210 Rec/7 TDs) last season– 2nd-worst Receptions Per TD among Power Conference Teams; Average: 11.7

Northwestern QBs fumbled 4 times in the Red Zone last season– 2nd-most among FBS Teams

Matchup Notes for Northwestern vs. Illinois