LSU vs Oklahoma Prediction, Odds & Best Prop Bets – NCAAF, Week 14

BetMGM Betting Nov 28, 2025, 10:30 AM

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Oklahoma head coach Brent Venables watches from the sideline during the first half of an NCAA college football game against Cincinnati, Saturday, Sept. 23, 2023, in Cincinnati. (AP Photo/Aaron Doster)

(AP Photo/Aaron Doster)

Oklahoma is a -10 point favorite vs. LSU
LSU vs. Oklahoma Total (Over/Under): 36.5 points
TV Channel: ABC

LSU (7-4) visit Gaylord Family Oklahoma Memorial Stadium to take on Oklahoma (9-2) on Nov. 29 in Norman, OK. Kickoff is scheduled for 3:30pm EST.

Oklahoma is a betting favorite in Week 14, with the spread sitting at -10 (-110).

The LSU vs. Oklahoma Over/Under is 36.5 total points.

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LSU vs. Oklahoma Odds, Spread, Over/Under:

	Spread	Total (O/U)	Moneyline
LSU	+10 -110	36.5 -110	325
Oklahoma	-10 -110	36.5 -110	-425

LSU vs Oklahoma Prediction:

The winning team model predicts Oklahoma will win this game with 76.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both LSU and Oklahoma, key player performances this season and recent team trends.

LSU vs Oklahoma Spread Prediction:

Based on recent against-the-spread trends, the model predicts LSU will cover the spread with 58.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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LSU Best Bets Today

LSU has hit the Team Total Under in 8 of their last 11 games (+4.82 Units / 41% ROI)
LSU has hit the 1H Moneyline in 8 of their last 12 games (+4.15 Units / 4% ROI)
LSU has hit the Moneyline in 7 of their last 11 games (+4.10 Units / 9% ROI)
LSU has hit the Game Total Under in 8 of their last 12 games (+3.60 Units / 27% ROI)
LSU has hit the 1H Game Total Under in 7 of their last 12 games (+1.40 Units / 10% ROI)

Oklahoma Best Bets Today

Oklahoma has hit the 1H Moneyline in 10 of their last 13 games (+8.10 Units / 1% ROI)
Oklahoma has hit the Game Total Under in 10 of their last 13 games (+6.70 Units / 47% ROI)
Oklahoma has hit the Team Total Under in 5 of their last 6 games at home (+5.00 Units / 72% ROI)
Oklahoma has hit the 1Q Moneyline in 8 of their last 12 games (+4.20 Units / 7% ROI)
Oklahoma has hit the 1H Game Total Under in 5 of their last 6 games at home (+3.85 Units / 56% ROI)

LSU Against the Spread (ATS) Record

LSU is 3-7 against the spread this college football season (-4.65 Units / -42.47% ROI).

LSU is 5-4 when betting on the Moneyline for +1.75 Units / 4.26% ROI
LSU is 2-8 when betting the Over for -6.8 Units / -61.82% ROI
LSU is 8-2 when betting the Under for +5.8 Units / 52.73% ROI

Oklahoma Against the Spread (ATS) Record

Oklahoma iss 7-4 against the spread this college football season (+2.6 Units / 21.49% ROI).

Oklahoma is 7-2 when betting on the Moneyline for +5.35 Units / 14.04% ROI
Oklahoma is 2-9 when betting the Over for -7.9 Units / -65.29% ROI
Oklahoma is 9-2 when betting the Under for +6.8 Units / 56.2% ROI

LSU: Keys to the Game vs. Oklahoma

Oklahoma has tackled opponents for a loss on 91 of 331 rushing attempts (28% TFL%) this season– best in the SEC; Average: 18%.

Oklahoma has tackled opponents for a loss on 91 of 331 rushing attempts (28% TFL%) this season– best in FBS; Average: 15%.

Oklahoma has tackled opponents for a loss on 91 of 331 rushing attempts (28% TFL%) this season– best among Power Conference Teams; Average: 16%.

Oklahoma has tackled opponents for a loss on 7 of 24 rushing attempts (29% TFL%) on 3rd and short this season– 2nd-best in FBS; Average: 11%.

Oklahoma has tackled opponents for a loss on 12 of 37 rushing attempts (32% TFL%) in the Red Zone this season– best in the SEC; Average: 15%.

Oklahoma: Keys to the Game vs. LSU

LSU has allowed a Completion Pct of just 20% (2 completions/10 attempts) on 3rd and short this season– best in the SEC; Average: 63%

LSU allowed a Completion Pct of just 31% (8 completions/26 attempts) in the Red Zone last season– best among Power Conference Teams; Average: 53%

LSU has allowed a Completion Pct of just 20% (2 completions/10 attempts) on 3rd and short this season– T-3rd-best in FBS; Average: 64%

LSU allowed opponents to catch just 8 of 26 passes (31% Reception Pct) in the Red Zone last season– best in FBS; Average: 54%

LSU has allowed a Completion Pct of just 20% (2 completions/10 attempts) on 3rd and short this season– T-2nd-best among Power Conference Teams; Average: 62%

Matchup Notes for LSU vs. Oklahoma