- Mississippi is a -1.5 point favorite vs. LSU
- LSU vs. Ole Miss Total (Over/Under): 54.5 points
- TV Channel: ABC
LSU (4-0) visit Vaught-Hemingway Stadium to take on Ole Miss (4-0) on Sep. 27 in University, MS. Kickoff is scheduled for 3:30pm EDT.
Mississippi is a betting favorite in Week 5, with the spread sitting at -1.5 (-105).
The LSU vs. Ole Miss Over/Under is 54.5 total points.
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LSU vs. Ole Miss Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| LSU | +1.5 -115 | 54.5 -105 | -105 |
| Ole Miss | -1.5 -105 | 54.5 -115 | -115 |
LSU vs Ole Miss Prediction:
The winning team model predicts LSU will win this game with 54.6% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both LSU and Mississippi, key player performances this season and recent team trends.
LSU vs Ole Miss Spread Prediction:
Based on recent against-the-spread trends, the model predicts LSU will cover the spread with 51.3% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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LSU Best Bets Today
- LSU has hit the Moneyline in 8 of their last 11 games (+6.15 Units / 20% ROI)
- LSU has hit the Game Total Under in 9 of their last 12 games (+5.70 Units / 43% ROI)
- LSU has hit the 1H Game Total Under in 9 of their last 12 games (+5.70 Units / 42% ROI)
- LSU has hit the 1H Moneyline in 8 of their last 11 games (+5.20 Units / 6% ROI)
- LSU have covered the Spread in 7 of their last 12 games (+1.50 Units / 11% ROI)
Ole Miss Best Bets Today
- Ole Miss has hit the 1H Game Total Under in 6 of their last 8 games at home (+3.70 Units / 41% ROI)
- Ole Miss has hit the Game Total Under in 8 of their last 13 games (+2.50 Units / 18% ROI)
- Ole Miss have covered the Spread in 5 of their last 8 games at home (+1.70 Units / 19% ROI)
- Ole Miss has hit the 1Q Game Total Over in 5 of their last 8 games at home (+1.50 Units / 16% ROI)
LSU Against the Spread (ATS) Record
LSU is 2-1 against the spread this college football season (+0.9 Units / 27.27% ROI).
- LSU is 2-0 when betting on the Moneyline for +2.75 Units / 88.71% ROI
- LSU is 0-3 when betting the Over for -3.3 Units / -100% ROI
- LSU is 3-0 when betting the Under for +3 Units / 90.91% ROI
Ole Miss Against the Spread (ATS) Record
Mississippi iss 3-1 against the spread this college football season (+1.9 Units / 43.18% ROI).
- Ole Miss is 3-0 when betting on the Moneyline for +3 Units / 32.97% ROI
- Ole Miss is 3-1 when betting the Over for +1.9 Units / 43.18% ROI
- Ole Miss is 1-3 when betting the Under for -2.3 Units / -52.27% ROI
LSU: Keys to the Game vs. Ole Miss
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — best among SEC skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — 5th-best among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — T-21st-best among FBS defenses.
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — 4th-best among FBS skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s offense has thrown for 1,098 passing yards in 4 games (274.5 YPG) this season — 31st-best among FBS offenses. Ole Miss’s defense has allowed just 166.2 passing yards per game this season — 25th-best among FBS defenses.
Ole Miss: Keys to the Game vs. LSU
Ole Miss QBs had 42 completions for 20 or more yards on 1st down last season– most among FBS Teams
Ole Miss have thrown 3 TDs and no interceptions in the 4th quarter this season– T-18th-best among FBS Offenses; Average: 2.0
Ole Miss Skill Players have averaged 24.1 yards per reception (241 yards/10 catches) in the 4th quarter this season– best among SEC Teams; Average: 12.7
Ole Miss Skill Players have averaged 15.8 yards per reception (5,860 yards/371 catches) since the 2024 season– best among SEC Teams; Average: 12.9
Ole Miss’s offense has thrown for 20 or more yards on 21.2% of 118 attempts this season — 2nd-best among FBS offenses. LSU’s defense allowed 20+ yards on just 5.2% of attempts this season — 8th-best among FBS defenses.
Matchup Notes for LSU vs. Ole Miss
Ole Miss QBs had 42 completions for 20 or more yards on 1st down last season– most among FBS Teams
Ole Miss have thrown 3 TDs and no interceptions in the 4th quarter this season– T-18th-best among FBS Offenses; Average: 2.0
Ole Miss Skill Players have averaged 24.1 yards per reception (241 yards/10 catches) in the 4th quarter this season– best among SEC Teams; Average: 12.7
Ole Miss Skill Players have averaged 15.8 yards per reception (5,860 yards/371 catches) since the 2024 season– best among SEC Teams; Average: 12.9
Ole Miss’s offense has thrown for 20 or more yards on 21.2% of 118 attempts this season — 2nd-best among FBS offenses. LSU’s defense allowed 20+ yards on just 5.2% of attempts this season — 8th-best among FBS defenses.
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — best among SEC skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — 5th-best among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — T-21st-best among FBS defenses.
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — 4th-best among FBS skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s offense has thrown for 1,098 passing yards in 4 games (274.5 YPG) this season — 31st-best among FBS offenses. Ole Miss’s defense has allowed just 166.2 passing yards per game this season — 25th-best among FBS defenses.
LSU Offensive Stats & Trends
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — best among SEC skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — 5th-best among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — T-21st-best among FBS defenses.
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — 4th-best among FBS skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s offense has thrown for 1,098 passing yards in 4 games (274.5 YPG) this season — 31st-best among FBS offenses. Ole Miss’s defense has allowed just 166.2 passing yards per game this season — 25th-best among FBS defenses.
Ole Miss Offensive Stats & Trends
Ole Miss QBs had 42 completions for 20 or more yards on 1st down last season– most among FBS Teams
Ole Miss have thrown 3 TDs and no interceptions in the 4th quarter this season– T-18th-best among FBS Offenses; Average: 2.0
Ole Miss Skill Players have averaged 24.1 yards per reception (241 yards/10 catches) in the 4th quarter this season– best among SEC Teams; Average: 12.7
Ole Miss Skill Players have averaged 15.8 yards per reception (5,860 yards/371 catches) since the 2024 season– best among SEC Teams; Average: 12.9
Ole Miss’s offense has thrown for 20 or more yards on 21.2% of 118 attempts this season — 2nd-best among FBS offenses. LSU’s defense allowed 20+ yards on just 5.2% of attempts this season — 8th-best among FBS defenses.
LSU Defensive Stats & Trends
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — best among SEC skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — 5th-best among SEC defenses.
LSU’s TEs has 18 receptions in 4 games (4.5 per game) this season — 4th-best among SEC TEs. Ole Miss’s defense has allowed just 15.0 receptions per game this season — T-21st-best among FBS defenses.
LSU has 437 receptions in 17 games (25.7 per game) since the 2024 season — 4th-best among FBS skill players. Ole Miss’s defense has allowed 19.2 receptions per game since the 2024 season — 4th-worst among SEC defenses.
LSU’s offense has thrown for 1,098 passing yards in 4 games (274.5 YPG) this season — 31st-best among FBS offenses. Ole Miss’s defense has allowed just 166.2 passing yards per game this season — 25th-best among FBS defenses.
Ole Miss Defensive Stats & Trends
Ole Miss QBs had 42 completions for 20 or more yards on 1st down last season– most among FBS Teams
Ole Miss have thrown 3 TDs and no interceptions in the 4th quarter this season– T-18th-best among FBS Offenses; Average: 2.0
Ole Miss Skill Players have averaged 24.1 yards per reception (241 yards/10 catches) in the 4th quarter this season– best among SEC Teams; Average: 12.7
Ole Miss Skill Players have averaged 15.8 yards per reception (5,860 yards/371 catches) since the 2024 season– best among SEC Teams; Average: 12.9
Ole Miss’s offense has thrown for 20 or more yards on 21.2% of 118 attempts this season — 2nd-best among FBS offenses. LSU’s defense allowed 20+ yards on just 5.2% of attempts this season — 8th-best among FBS defenses.
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