- Louisville is a -14 point favorite vs. James Madison
- James Madison vs. Louisville Total (Over/Under): 57.5 points
- TV Channel: ESPN2
James Madison (1-0) visit L&N Federal Credit Union Stadium to take on Louisville (1-0) on Sep. 5 in Louisville, KY. Kickoff is scheduled for 7:00pm EDT.
Louisville is a betting favorite in Week 2, with the spread sitting at -14 (-110).
The James Madison vs. Louisville Over/Under is 57.5 total points.
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James Madison vs. Louisville Odds, Spread, Over/Under:
| Spread | Total (O/U) | Moneyline | |
| James Madison | +14 -110 | 57.5 -110 | +425 |
| Louisville | -14 -110 | 57.5 -110 | -600 |
James Madison vs Louisville Prediction:
The winning team model predicts Louisville will win this game with 85.1% confidence, based on game simulations, offensive & defensive matchups and recent game results.
This winning team prediction factors in up-to-date player injuries for both James Madison and Louisville, key player performances this season and recent team trends.
James Madison vs Louisville Spread Prediction:
Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 70.3% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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James Madison Best Bets & Trends for ATS, Moneyline & Totals
- James Madison has hit the Game Total Under in 8 of their last 13 games (+3.60 Units / 25% ROI)
- James Madison have covered the 1Q Spread in 4 of their last 5 games (+3.05 Units / 58% ROI)
- James Madison has hit the 1Q Moneyline in their last 3 games (+3.00 Units / 58% ROI)
- James Madison has hit the 1H Game Total Over in 4 of their last 5 away games (+2.80 Units / 50% ROI)
- James Madison has hit the 1Q Game Total Over in 6 of their last 10 games (+1.40 Units / 12% ROI)
Louisville Best Bets & Trends for ATS, Moneyline & Totals
- Louisville has hit the Game Total Over in 9 of their last 13 games (+4.60 Units / 32% ROI)
- Louisville has hit the 1H Game Total Over in 5 of their last 6 games at home (+3.85 Units / 56% ROI)
- Louisville have covered the 1Q Spread in their last 3 games (+3.00 Units / 83% ROI)
- Louisville has hit the 1Q Moneyline in their last 3 games (+3.00 Units / 67% ROI)
- Louisville has hit the Moneyline in their last 3 games (+3.00 Units / 53% ROI)
We’ve highlighted some favorite college football player prop bets for James Madison players, looking at profitable historical betting trends:
James Madison: Keys to the Game vs. Louisville
James Madison is 15-1 (.938) when allowing less than 3 sacks since the 2023 season– best among Non-Power Conference Teams; Average: .582
James Madison is 16-2 (.889) when committing less than 60 yards in penalties since the 2023 season– best among Non-Power Conference Teams; Average: .469
James Madison is undefeated (6-0) when the opposing team commits 60 yards or more in penalties. since the 2023 season– best among Non-Power Conference Teams; Average: .486
James Madison was 7-1 (.875) when they have committed less than 60 yards in penalties in the 2024 season– T-3rd-best among Non-Power Conference Teams; Average: .476
Louisville: Keys to the Game vs. James Madison
Louisville is 11-5 (.688) when sacking the QB less than 3 times since the 2023 season– T-13th-best in FBS; Average: .426
Louisville is 13-6 (.684) when having a turnover margin within one of the opposing team since the 2023 season– T-30th-best in FBS; Average: .531
Louisville is 18-6 (.750) when allowing less than 50% of third down conversion opportunities since the 2023 season– 26th-best in FBS; Average: .603
Louisville is 16-7 (.696) when rushing at least 4 yards in a play 10 or more times since the 2023 season– 33rd-best in FBS; Average: .576
Matchup Notes for James Madison vs. Louisville
Louisville’s RBs has rushed for 180 yards on 20 carries (9.0 YPC) this season — 4th-best among FBS RBs. James Madison’s defense have allowed just 1.9 YPC to RBs this season — T-6th-best among FBS defenses.
Louisville’s RBs has rushed for 180 yards on 20 carries (9.0 YPC) this season — 4th-best among FBS RBs. James Madison’s defense have allowed just 2.1 YPC this season — 27th-best among FBS defenses.
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James Madison’s RBs has rushed for 240 yards on 30 carries (8.0 YPC) this season — T-8th-best among FBS RBs. Louisville’s defense have allowed just 2.6 YPC to RBs this season — 26th-best among FBS defenses.
James Madison’s RBs has rushed for 240 yards on 30 carries (8.0 YPC) this season — T-8th-best among FBS RBs. Louisville’s defense have allowed just 1.9 YPC this season — 4th-best among ACC defenses.
James Madison’s RBs has rushed for 240 yards on 30 carries (8.0 YPC) this season — T-8th-best among FBS RBs. Louisville’s defense have allowed just 1.9 YPC this season — T-21st-best among FBS defenses.
James Madison Offensive Stats & Trends
James Madison RBs have caught 8 touchdown passes in the Red Zone since the 2023 season– 2nd-most among FBS Teams
James Madison RBs have picked up first downs on 7 receptions in the Red Zone since the 2023 season– T-2nd-most among FBS Teams
James Madison WRs averaged just 8.7 yards per reception (208 yards/24 catches) in the 4th quarter in the 2024 season– 3rd-worst among FBS Teams; Average: 13.1
James Madison WRs have averaged just 8.2 yards per reception (212 yards/26 catches) in the 4th quarter since the 2024 season– worst among FBS Teams; Average: 13.2
James Madison WRs have averaged just 8.8 yards per reception (97 yards/11 catches) this season– T-18th-worst among FBS Teams; Average: 12.5
Louisville Offensive Stats & Trends
Louisville RBs have averaged 9.0 Yards per Carry (180 yards/20 carries) this season– 4th-best among FBS Teams; Average: 5.1
Louisville TEs picked up first downs on 9 receptions in close and late situations in the 2024 season– T-2nd-most among FBS Teams
Louisville RBs have averaged 6.7 Yards per Carry (2,507 yards/376 carries) since the 2024 season– best among FBS Teams; Average: 5.1
Louisville RBs have averaged 12.3 Yards per Carry (148 yards/12 carries) in the 1st half this season– 4th-best among FBS Teams; Average: 5.2
Louisville RBs have averaged 6.2 Yards per Carry (4,425 yards/714 carries) since the 2023 season– T-4th-best among FBS Teams; Average: 5.1
James Madison Defensive Stats & Trends
James Madison has averaged 3.00 interceptions per game (3/1) this season– T-3rd-best in FBS; Average: 0.70
James Madison has tackled opponents for a loss on 12 of 51 rushing attempts (23% TFL%) on 3rd and short since the 2023 season– best in FBS; Average: 11%.
James Madison has tackled opponents for a loss on 12 of 51 rushing attempts (23% TFL%) on 3rd and short since the 2023 season– best among Non-Power Conference Teams; Average: 11%.
James Madison did not record a sack (38 pass attempts) in the Red Zone in the 2023 season– T-worst among Non-Power Conference Teams; Average: 16.4
James Madison has averaged 3.00 interceptions per game (3/1) this season– 2nd-best among Non-Power Conference Teams; Average: 0.69
Louisville Defensive Stats & Trends
Louisville has sacked opposing QBs on 29% of pass attempts (4/14) this season– best in FBS; Average: 7%
Louisville has sacked opposing QBs on 29% of pass attempts (4/14) this season– best among Power Conference Teams; Average: 7%
Louisville has allowed opponents to catch just 5 of 14 passes (36% Reception Pct) this season– 2nd-best among Power Conference Teams; Average: 59%
Louisville has allowed a Completion Pct of just 36% (5 completions/14 attempts) this season– 2nd-best among Power Conference Teams; Average: 58%
Louisville has allowed a Completion Pct of just 46% (51 completions/111 attempts) in close and late situations since the 2023 season– 2nd-best among Power Conference Teams; Average: 58%
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