Indiana vs Iowa Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 5

Fans cheer before an NCAA college football game between Iowa and North Texas at Kinnick Stadium in Iowa City, Iowa, Sept. 16, 2017. Iowa will attempt to set the all-time women's basketball attendance record when it hosts DePaul in an outdoor exhibition at 69,000-seat Kinnick Stadium on Oct. 15, the school announced Thursday, Aug. 10, 2023.
(AP Photo/Charlie Neibergall)
  • Indiana is a -7.5 point favorite vs. Iowa
  • Indiana vs. Iowa Total (Over/Under): 48.5 points
  • TV Channel: PEAC

Indiana (4-0) visit Kinnick Stadium to take on Iowa (3-1) on Sep. 27 in Iowa City, IA. Kickoff is scheduled for 3:30pm EDT.

Indiana is a betting favorite in Week 5, with the spread sitting at -7.5 (-110).

The Indiana vs. Iowa Over/Under is 48.5 total points.

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Indiana vs. Iowa Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Indiana-7.5 -11048.5 -110-300
Iowa +7.5 -11048.5 -110240

Indiana vs Iowa Prediction:

The winning team model predicts Indiana will win this game with 70.0% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Indiana and Iowa, key player performances this season and recent team trends.

Indiana vs Iowa Spread Prediction:

Based on recent against-the-spread trends, the model predicts Indiana will cover the spread with 61.3% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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Indiana Against the Spread (ATS) Record

Indiana is 3-1 against the spread this college football season (+1.9 Units / 43.18% ROI).

  • Indiana is 3-0 when betting on the Moneyline for +3 Units / 4.03% ROI
  • Indiana is 3-1 when betting the Over for +1.9 Units / 43.18% ROI
  • Indiana is 1-3 when betting the Under for -2.3 Units / -52.27% ROI

Iowa Against the Spread (ATS) Record

Iowa iss 2-1 against the spread this college football season (+0.94 Units / 21.81% ROI).

  • Iowa is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
  • Iowa is 2-2 when betting the Over for -0.2 Units / -4.55% ROI
  • Iowa is 2-2 when betting the Under for -0.2 Units / -4.51% ROI

Indiana: Keys to the Game vs. Iowa

Indiana WRs have caught 12 touchdown passes in the Red Zone this season– most among FBS Teams

Indiana’s QBs has thrown for 1,119 passing yards in 4 games (279.8 YPG) this season — 27th-best among FBS teams. Iowa’s defense has allowed just 172.8 passing yards per game this season — 32nd-best among FBS defenses.

Indiana has averaged 13.6 yards after the catch since the 2024 season — best among Big Ten skill players. Iowa’s defense has allowed just 7.8 RAC to TEs since the 2024 season — 5th-best among FBS defenses.

Indiana RBs have averaged 262.2 rushing yards per game (1,049/4) this season– best among FBS Teams; Average: 132.7

Indiana WRs caught 4 touchdown passes in the Red Zone last week– most among FBS Teams

Iowa: Keys to the Game vs. Indiana

Iowa Skill Players have averaged just 13.8 receptions per game (55/4) this season– worst among Big Ten Teams; Average: 19.5

Iowa TEs have just one touchdown on 70 receptions since the 2024 season– worst Receptions Per TD among Power Conference Teams; Average: 9.8

Iowa has gained 551 yards on 55 receptions (just 10.0 YPR) this season — T-5th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 Yards Per Reception this season — T-5th-best among Big Ten defenses.

Iowa’s offense has thrown for 551 passing yards in 4 games (just 137.8 YPG) this season — 8th-worst among FBS offenses. Indiana’s defense has allowed just 118.8 passing yards per game this season — 3rd-best among Big Ten defenses.

Iowa has averaged just 10.4 yards after the catch since the 2024 season — T-4th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 RAC since the 2024 season — best among Big Ten defenses.

Matchup Notes for Indiana vs. Iowa

Iowa Skill Players have averaged just 13.8 receptions per game (55/4) this season– worst among Big Ten Teams; Average: 19.5

Iowa TEs have just one touchdown on 70 receptions since the 2024 season– worst Receptions Per TD among Power Conference Teams; Average: 9.8

Iowa has gained 551 yards on 55 receptions (just 10.0 YPR) this season — T-5th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 Yards Per Reception this season — T-5th-best among Big Ten defenses.

Iowa’s offense has thrown for 551 passing yards in 4 games (just 137.8 YPG) this season — 8th-worst among FBS offenses. Indiana’s defense has allowed just 118.8 passing yards per game this season — 3rd-best among Big Ten defenses.

Iowa has averaged just 10.4 yards after the catch since the 2024 season — T-4th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 RAC since the 2024 season — best among Big Ten defenses.

Indiana WRs have caught 12 touchdown passes in the Red Zone this season– most among FBS Teams

Indiana’s QBs has thrown for 1,119 passing yards in 4 games (279.8 YPG) this season — 27th-best among FBS teams. Iowa’s defense has allowed just 172.8 passing yards per game this season — 32nd-best among FBS defenses.

Indiana has averaged 13.6 yards after the catch since the 2024 season — best among Big Ten skill players. Iowa’s defense has allowed just 7.8 RAC to TEs since the 2024 season — 5th-best among FBS defenses.

Indiana RBs have averaged 262.2 rushing yards per game (1,049/4) this season– best among FBS Teams; Average: 132.7

Indiana WRs caught 4 touchdown passes in the Red Zone last week– most among FBS Teams

Indiana Offensive Stats & Trends

Indiana WRs have caught 12 touchdown passes in the Red Zone this season– most among FBS Teams

Indiana’s QBs has thrown for 1,119 passing yards in 4 games (279.8 YPG) this season — 27th-best among FBS teams. Iowa’s defense has allowed just 172.8 passing yards per game this season — 32nd-best among FBS defenses.

Indiana has averaged 13.6 yards after the catch since the 2024 season — best among Big Ten skill players. Iowa’s defense has allowed just 7.8 RAC to TEs since the 2024 season — 5th-best among FBS defenses.

Indiana RBs have averaged 262.2 rushing yards per game (1,049/4) this season– best among FBS Teams; Average: 132.7

Indiana WRs caught 4 touchdown passes in the Red Zone last week– most among FBS Teams

Iowa Offensive Stats & Trends

Iowa Skill Players have averaged just 13.8 receptions per game (55/4) this season– worst among Big Ten Teams; Average: 19.5

Iowa TEs have just one touchdown on 70 receptions since the 2024 season– worst Receptions Per TD among Power Conference Teams; Average: 9.8

Iowa has gained 551 yards on 55 receptions (just 10.0 YPR) this season — T-5th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 Yards Per Reception this season — T-5th-best among Big Ten defenses.

Iowa’s offense has thrown for 551 passing yards in 4 games (just 137.8 YPG) this season — 8th-worst among FBS offenses. Indiana’s defense has allowed just 118.8 passing yards per game this season — 3rd-best among Big Ten defenses.

Iowa has averaged just 10.4 yards after the catch since the 2024 season — T-4th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 RAC since the 2024 season — best among Big Ten defenses.

Indiana Defensive Stats & Trends

Indiana WRs have caught 12 touchdown passes in the Red Zone this season– most among FBS Teams

Indiana’s QBs has thrown for 1,119 passing yards in 4 games (279.8 YPG) this season — 27th-best among FBS teams. Iowa’s defense has allowed just 172.8 passing yards per game this season — 32nd-best among FBS defenses.

Indiana has averaged 13.6 yards after the catch since the 2024 season — best among Big Ten skill players. Iowa’s defense has allowed just 7.8 RAC to TEs since the 2024 season — 5th-best among FBS defenses.

Indiana RBs have averaged 262.2 rushing yards per game (1,049/4) this season– best among FBS Teams; Average: 132.7

Indiana WRs caught 4 touchdown passes in the Red Zone last week– most among FBS Teams

Iowa Defensive Stats & Trends

Iowa Skill Players have averaged just 13.8 receptions per game (55/4) this season– worst among Big Ten Teams; Average: 19.5

Iowa TEs have just one touchdown on 70 receptions since the 2024 season– worst Receptions Per TD among Power Conference Teams; Average: 9.8

Iowa has gained 551 yards on 55 receptions (just 10.0 YPR) this season — T-5th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 Yards Per Reception this season — T-5th-best among Big Ten defenses.

Iowa’s offense has thrown for 551 passing yards in 4 games (just 137.8 YPG) this season — 8th-worst among FBS offenses. Indiana’s defense has allowed just 118.8 passing yards per game this season — 3rd-best among Big Ten defenses.

Iowa has averaged just 10.4 yards after the catch since the 2024 season — T-4th-worst among Power 5 skill players. Indiana’s defense has allowed just 9.3 RAC since the 2024 season — best among Big Ten defenses.


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