Connecticut vs Buffalo U Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 5

Buffalo head coach Pete Lembo, left, watches his team during the second half of an NCAA college football game against Northern Illinois on Saturday, Sept. 21, 2024, in DeKalb, Ill. (AP Photo/Charles Rex Arbogast)
(AP Photo/Charles Rex Arbogast)
  • Connecticut is a -4 point favorite vs. Buffalo U
  • Connecticut vs. Buffalo Total (Over/Under): 49.5 points
  • TV Channel: ESPN+

Connecticut (2-2) visit UB Stadium to take on Buffalo (2-2) on Sep. 27 in Buffalo, NY. Kickoff is scheduled for 3:30pm EDT.

Connecticut is a betting favorite in Week 5, with the spread sitting at -4 (-110).

The Connecticut vs. Buffalo Over/Under is 49.5 total points.

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Connecticut vs. Buffalo Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Connecticut-4 -11049.5 -110-180
Buffalo +4 -11049.5 -110145

Connecticut vs Buffalo Prediction:

The winning team model predicts UConn will win this game with 56.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Connecticut and Buffalo U, key player performances this season and recent team trends.

Connecticut vs Buffalo Spread Prediction:

Based on recent against-the-spread trends, the model predicts UConn will cover the spread with 54.3% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • UConn has hit the Moneyline in 9 of their last 13 games (+2.90 Units / 4% ROI)
  • UConn has hit the 1Q Game Total Over in 4 of their last 6 away games (+1.90 Units / 30% ROI)
  • UConn has hit the 1H Game Total Over in 4 of their last 6 away games (+1.80 Units / 27% ROI)
  • UConn has hit the Game Total Over in 7 of their last 13 games (+1.50 Units / 10% ROI)
  • UConn have covered the 1Q Spread in 6 of their last 10 games (+1.40 Units / 12% ROI)
  • Buffalo have covered the 1Q Spread in 8 of their last 11 games (+4.80 Units / 35% ROI)
  • Buffalo has hit the Game Total Over in 9 of their last 13 games (+4.55 Units / 32% ROI)
  • Buffalo has hit the Moneyline in 7 of their last 12 games (+3.00 Units / 6% ROI)
  • Buffalo has hit the 1H Game Total Under in 8 of their last 13 games (+2.45 Units / 17% ROI)
  • Buffalo has hit the 1Q Game Total Under in 7 of their last 11 games (+2.40 Units / 19% ROI)

Connecticut Against the Spread (ATS) Record

Connecticut is against the spread this college football season ( Units / ROI).

  • Connecticut is when betting on the Moneyline for Units / ROI
  • Connecticut is when betting the Over for Units / ROI
  • Connecticut is when betting the Under for Units / ROI

Buffalo Against the Spread (ATS) Record

Buffalo U iss 2-2 against the spread this college football season (-0.2 Units / -4.55% ROI).

  • Buffalo is 1-2 when betting on the Moneyline for -2.1 Units / -8.37% ROI
  • Buffalo is 2-2 when betting the Over for -0.2 Units / -4.55% ROI
  • Buffalo is 2-2 when betting the Under for -0.2 Units / -4.55% ROI

Connecticut: Keys to the Game vs. Buffalo

UConn RBs have averaged 14.0 yards from scrimmage per touch (293 yards / 21 touches) on 3rd down this season– 3rd-best among FBS Teams; Average: 6.3

UConn’s RBs has rushed for 3,247 yards on 516 carries (6.3 YPC) since the 2024 season — T-5th-best among FBS RBs. Buffalo’s defense have allowed just 3.8 YPC since the 2024 season — T-35th-best among FBS defenses.

UConn WRs had 4 receptions in the Red Zone last week– T-3rd-most among FBS Teams

UConn’s WRs has averaged 23.2 targets per game since the 2024 season — 34th-highest among FBS WRs. Buffalo’s defense has allowed 13.5 receptions per game to WRs since the 2024 season — T-28th-worst among FBS defenses.

UConn WRs have 11 receptions in the Red Zone this season– T-4th-most among FBS Teams

Buffalo: Keys to the Game vs. Connecticut

Buffalo’s offense has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS offenses. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo’s QBs has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS teams. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo has 258 receptions in 17 games (just 15.2 per game) since the 2024 season — T-21st-worst among FBS skill players. UConn’s defense has allowed 21.2 receptions per game since the 2024 season — T-13th-worst among FBS defenses.

Buffalo have caught just 33 of 80 passes (41% Reception Pct) in the 4th quarter since the 2024 season– worst among FBS Offenses; Average: 60%

Buffalo RBs averaged 17.6 yards per reception (88 yards/5 catches) in the 4th quarter last season– T-3rd-best among FBS Teams; Average: 8.1

Matchup Notes for Connecticut vs. Buffalo

Buffalo’s offense has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS offenses. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo’s QBs has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS teams. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo has 258 receptions in 17 games (just 15.2 per game) since the 2024 season — T-21st-worst among FBS skill players. UConn’s defense has allowed 21.2 receptions per game since the 2024 season — T-13th-worst among FBS defenses.

Buffalo have caught just 33 of 80 passes (41% Reception Pct) in the 4th quarter since the 2024 season– worst among FBS Offenses; Average: 60%

Buffalo RBs averaged 17.6 yards per reception (88 yards/5 catches) in the 4th quarter last season– T-3rd-best among FBS Teams; Average: 8.1

UConn RBs have averaged 14.0 yards from scrimmage per touch (293 yards / 21 touches) on 3rd down this season– 3rd-best among FBS Teams; Average: 6.3

UConn’s RBs has rushed for 3,247 yards on 516 carries (6.3 YPC) since the 2024 season — T-5th-best among FBS RBs. Buffalo’s defense have allowed just 3.8 YPC since the 2024 season — T-35th-best among FBS defenses.

UConn WRs had 4 receptions in the Red Zone last week– T-3rd-most among FBS Teams

UConn’s WRs has averaged 23.2 targets per game since the 2024 season — 34th-highest among FBS WRs. Buffalo’s defense has allowed 13.5 receptions per game to WRs since the 2024 season — T-28th-worst among FBS defenses.

UConn WRs have 11 receptions in the Red Zone this season– T-4th-most among FBS Teams

Connecticut Offensive Stats & Trends

UConn RBs have averaged 14.0 yards from scrimmage per touch (293 yards / 21 touches) on 3rd down this season– 3rd-best among FBS Teams; Average: 6.3

UConn’s RBs has rushed for 3,247 yards on 516 carries (6.3 YPC) since the 2024 season — T-5th-best among FBS RBs. Buffalo’s defense have allowed just 3.8 YPC since the 2024 season — T-35th-best among FBS defenses.

UConn WRs had 4 receptions in the Red Zone last week– T-3rd-most among FBS Teams

UConn’s WRs has averaged 23.2 targets per game since the 2024 season — 34th-highest among FBS WRs. Buffalo’s defense has allowed 13.5 receptions per game to WRs since the 2024 season — T-28th-worst among FBS defenses.

UConn WRs have 11 receptions in the Red Zone this season– T-4th-most among FBS Teams

Buffalo Offensive Stats & Trends

Buffalo’s offense has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS offenses. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo’s QBs has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS teams. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo has 258 receptions in 17 games (just 15.2 per game) since the 2024 season — T-21st-worst among FBS skill players. UConn’s defense has allowed 21.2 receptions per game since the 2024 season — T-13th-worst among FBS defenses.

Buffalo have caught just 33 of 80 passes (41% Reception Pct) in the 4th quarter since the 2024 season– worst among FBS Offenses; Average: 60%

Buffalo RBs averaged 17.6 yards per reception (88 yards/5 catches) in the 4th quarter last season– T-3rd-best among FBS Teams; Average: 8.1

Connecticut Defensive Stats & Trends

UConn RBs have averaged 14.0 yards from scrimmage per touch (293 yards / 21 touches) on 3rd down this season– 3rd-best among FBS Teams; Average: 6.3

UConn’s RBs has rushed for 3,247 yards on 516 carries (6.3 YPC) since the 2024 season — T-5th-best among FBS RBs. Buffalo’s defense have allowed just 3.8 YPC since the 2024 season — T-35th-best among FBS defenses.

UConn WRs had 4 receptions in the Red Zone last week– T-3rd-most among FBS Teams

UConn’s WRs has averaged 23.2 targets per game since the 2024 season — 34th-highest among FBS WRs. Buffalo’s defense has allowed 13.5 receptions per game to WRs since the 2024 season — T-28th-worst among FBS defenses.

UConn WRs have 11 receptions in the Red Zone this season– T-4th-most among FBS Teams

Buffalo Defensive Stats & Trends

Buffalo’s offense has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS offenses. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo’s QBs has thrown for 711 passing yards in 4 games (just 177.8 YPG) this season — 25th-worst among FBS teams. UConn’s defense has allowed 259.8 passing yards per game this season — 25th-worst among FBS defenses.

Buffalo has 258 receptions in 17 games (just 15.2 per game) since the 2024 season — T-21st-worst among FBS skill players. UConn’s defense has allowed 21.2 receptions per game since the 2024 season — T-13th-worst among FBS defenses.

Buffalo have caught just 33 of 80 passes (41% Reception Pct) in the 4th quarter since the 2024 season– worst among FBS Offenses; Average: 60%

Buffalo RBs averaged 17.6 yards per reception (88 yards/5 catches) in the 4th quarter last season– T-3rd-best among FBS Teams; Average: 8.1


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