Colorado vs TCU Prediction, Odds & Best Prop Bets – NCAAF, Week 6

BetMGM Betting Oct 02, 2025, 3:04 PM

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A general view of the exterior of Amon G. Carter Stadium before an NCAA college football game between TCU and Oklahoma State in Fort Worth, Texas, Saturday, Oct. 15, 2022.

(AP Photo/Sam Hodde)

TCU is a -13.5 point favorite vs. Colorado
Colorado vs. TCU Total (Over/Under): 57.5 points
TV Channel: FOX

Colorado (2-3) visit Amon G. Carter Stadium to take on TCU (3-1) on Oct. 4 in Fort Worth, TX. Kickoff is scheduled for 7:30pm EDT.

TCU is a betting favorite in Week 6, with the spread sitting at -13.5 (-115).

The Colorado vs. TCU Over/Under is 57.5 total points.

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Colorado vs. TCU Odds, Spread, Over/Under:

	Spread	Total (O/U)	Moneyline
Colorado	+13.5 -105	57.5 -105	400
TCU	-13.5 -115	57.5 -115	-550

Colorado vs TCU Prediction:

The winning team model predicts TCU will win this game with 79.4% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Colorado and TCU, key player performances this season and recent team trends.

Colorado vs TCU Spread Prediction:

Based on recent against-the-spread trends, the model predicts Colorado will cover the spread with 67.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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Colorado Best Bets Today

Colorado have covered the Spread in 9 of their last 13 games (+4.60 Units / 32% ROI)
Colorado has hit the 1Q Moneyline in 7 of their last 12 games (+2.50 Units / 10% ROI)
Colorado have covered the 1Q Spread in 7 of their last 13 games (+1.65 Units / 11% ROI)
Colorado has hit the Game Total Under in 7 of their last 13 games (+1.50 Units / 10% ROI)
Colorado has hit the Team Total Under in 3 of their last 5 games (+0.80 Units / 14% ROI)

TCU Best Bets Today

TCU have covered the 1Q Spread in 10 of their last 11 games (+9.05 Units / 72% ROI)
TCU has hit the 1Q Moneyline in 8 of their last 9 games (+8.00 Units / 22% ROI)
TCU have covered the 1H Spread in 10 of their last 12 games (+7.65 Units / 54% ROI)
TCU has hit the 1H Game Total Under in 8 of their last 12 games (+4.60 Units / 34% ROI)
TCU have covered the Spread in 7 of their last 12 games (+2.60 Units / 20% ROI)

Colorado Against the Spread (ATS) Record

Colorado is 3-2 against the spread this college football season (+0.8 Units / 14.55% ROI).

Colorado is 2-3 when betting on the Moneyline for -1 Units / -3.4% ROI
Colorado is 2-3 when betting the Over for -1.3 Units / -23.64% ROI
Colorado is 3-2 when betting the Under for +0.8 Units / 14.55% ROI

TCU Against the Spread (ATS) Record

TCU iss 2-1 against the spread this college football season (+0.9 Units / 20.45% ROI).

TCU is 2-1 when betting on the Moneyline for +1 Units / 19.8% ROI
TCU is 2-2 when betting the Over for -0.2 Units / -4.55% ROI
TCU is 2-2 when betting the Under for -0.2 Units / -4.55% ROI

Colorado: Keys to the Game vs. TCU

Colorado was undefeated (7-0) when rushing at least 4 yards in a play 10 or more times last season– T-best among Power Conference Teams; Average: .618

Colorado was 6-1 (.857) when averaging more than 5 yards on first down plays last season– T-13th-best in FBS; Average: .604

Colorado was undefeated (7-0) when rushing at least 4 yards in a play 10 or more times last season– T-best in FBS; Average: .575

Colorado was 2-4 (.333) when not forcing and recovering a fumble last season– T-13th-worst among Power Conference Teams; Average: .492

TCU: Keys to the Game vs. Colorado

Colorado WRs averaged 23.3 receptions per game (303/13) last season– best among Power Conference Teams; Average: 12.6

Colorado TEs have averaged just 6.6 yards per reception (93 yards/14 catches) since the 2024 season– worst among Big 12 Teams; Average: 11.1

Colorado have averaged 17.7 yards per completion (1,486 yards/84 completions) on 3rd down since the 2024 season– best among FBS Offenses; Average: 12.0

Colorado WRs averaged 23.3 receptions per game (303/13) last season– best among FBS Teams; Average: 12.3

Colorado WRs averaged 23.3 receptions per game (303/13) last season– best among Big 12 Teams; Average: 13.2

Matchup Notes for Colorado vs. TCU