Colorado vs Houston Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 3

Colorado head coach Deion Sanders in the first half of the team's spring practice NCAA college football game Saturday, April 22, 2023, in Boulder, Colo. (AP Photo/David Zalubowski)
(AP Photo/David Zalubowski)
  • Houston is a -4.5 point favorite vs. Colorado
  • Colorado vs. Houston Total (Over/Under): 45.5 points
  • TV Channel: ESPN

Colorado (1-1) visit TDECU Stadium to take on Houston (2-0) on Sep. 12 in Houston, TX. Kickoff is scheduled for 7:30pm EDT.

Houston is a betting favorite in Week 3, with the spread sitting at -4.5 (-110).

The Colorado vs. Houston Over/Under is 45.5 total points.

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Colorado vs. Houston Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Colorado++4.5 -11045.5 -115165
Houston -4.5 -11045.5 -105-200

Colorado vs Houston Prediction:

The winning team model predicts Houston will win this game with 88.8% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Colorado and Houston, key player performances this season and recent team trends.

Colorado vs Houston Spread Prediction:

Based on recent against-the-spread trends, the model predicts Houston will cover the spread with 77.4% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Colorado has hit the Moneyline in 9 of their last 13 games (+6.80 Units / 14% ROI)
  • Colorado have covered the Spread in 10 of their last 13 games (+6.70 Units / 47% ROI)
  • Colorado have covered the 1Q Spread in 8 of their last 13 games (+4.05 Units / 28% ROI)
  • Colorado has hit the 1Q Moneyline in 8 of their last 12 games (+3.60 Units / 15% ROI)
  • Colorado has hit the 1H Moneyline in 3 of their last 5 away games (+2.05 Units / 29% ROI)
  • Houston has hit the Moneyline in 6 of their last 12 games (+8.05 Units / 20% ROI)
  • Houston has hit the Game Total Under in their last 6 games at home (+6.00 Units / 91% ROI)
  • Houston have covered the 1H Spread in 5 of their last 6 games at home (+3.85 Units / 58% ROI)
  • Houston has hit the 1H Game Total Under in 5 of their last 6 games at home (+3.85 Units / 55% ROI)
  • Houston have covered the Spread in 4 of their last 6 games at home (+1.80 Units / 27% ROI)

Colorado Against the Spread (ATS) Record

Colorado is 1-1 against the spread this college football season (-0.1 Units / -4.55% ROI).

  • Colorado is 1-1 when betting on the Moneyline for +0 Units / 0% ROI
  • Colorado is 0-2 when betting the Over for -2.2 Units / -100% ROI
  • Colorado is 2-0 when betting the Under for +2 Units / 90.91% ROI

Houston Against the Spread (ATS) Record

Houston iss 2-0 against the spread this college football season (+2 Units / 90.91% ROI).

  • Houston is 2-0 when betting on the Moneyline for +2 Units / 7.02% ROI
  • Houston is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
  • Houston is 1-1 when betting the Under for -0.1 Units / -4.55% ROI

Colorado: Keys to the Game vs. Houston

Colorado was undefeated (7-0) when rushing at least 4 yards in a play 10 or more times last season– T-best in FBS; Average: .575

Colorado was 6-1 (.857) when averaging more than 5 yards on first down plays last season– T-13th-best in FBS; Average: .604

Colorado was undefeated (7-0) when rushing at least 4 yards in a play 10 or more times last season– T-best among Power Conference Teams; Average: .618

Colorado was 6-1 (.857) when averaging more than 5 yards on first down plays last season– 7th-best among Power Conference Teams; Average: .632

Houston: Keys to the Game vs. Colorado

Houston was 1-8 (.111) when throwing at least 1 interception last season– 3rd-worst among Power Conference Teams; Average: .443

Houston was winless (0-7) when allowing 100 or more rushing yards last season– T-worst in FBS; Average: .422

Houston was 4-7 (.364) when their opponent committed less than 60 yards in penalties last season– T-36th-worst in FBS; Average: .536

Houston was 1-5 (.167) when allowing more than 3 explosive runs last season– T-9th-worst among Power Conference Teams; Average: .459

Matchup Notes for Colorado vs. Houston

Houston’s offense has thrown for 340 passing yards in 2 games (just 170.0 YPG) this season — 33rd-worst among FBS offenses. Colorado’s defense has allowed 227.5 passing yards per game this season — 3rd-worst among Big 12 defenses.

Houston’s WRs has 120 receptions in 14 games (just 8.6 per game) since the 2024 season — 2nd-worst among Big 12 WRs. Colorado’s defense has allowed just 10.5 receptions per game to WRs since the 2024 season — T-26th-best among FBS defenses.

Houston has 211 receptions in 14 games (just 15.1 per game) since the 2024 season — T-21st-worst among FBS skill players. Colorado’s defense has allowed just 17.3 receptions per game since the 2024 season — 5th-best among Big 12 defenses.

Colorado’s TEs has gained 25 yards on 3 receptions (just 8.3 YPR) this season — 2nd-worst among Big 12 TEs. Houston’s defense has allowed just 5.6 Yards Per Reception this season — best among P5 defenses.

Colorado’s TEs has gained 25 yards on 3 receptions (just 8.3 YPR) this season — 2nd-worst among Big 12 TEs. Houston’s defense has allowed just 5.6 Yards Per Reception this season — best among Big 12 defenses.

Colorado’s WRs has 326 receptions in 15 games (21.7 per game) since the 2024 season — best among FBS WRs. Houston’s defense has allowed just 16.2 receptions per game since the 2024 season — 3rd-best among Big 12 defenses.

Colorado Offensive Stats & Trends

Colorado WRs averaged 23.3 receptions per game (303/13) last season– best among Power Conference Teams; Average: 12.6

Colorado WRs averaged 23.3 receptions per game (303/13) last season– best among FBS Teams; Average: 12.3

Colorado’s TEs has gained 25 yards on 3 receptions (just 8.3 YPR) this season — 2nd-worst among Big 12 TEs. Houston’s defense has allowed just 5.6 Yards Per Reception this season — best among P5 defenses.

Colorado’s TEs has gained 25 yards on 3 receptions (just 8.3 YPR) this season — 2nd-worst among Big 12 TEs. Houston’s defense has allowed just 5.6 Yards Per Reception this season — best among Big 12 defenses.

Colorado’s WRs has 326 receptions in 15 games (21.7 per game) since the 2024 season — best among FBS WRs. Houston’s defense has allowed just 16.2 receptions per game since the 2024 season — 3rd-best among Big 12 defenses.

Houston Offensive Stats & Trends

Houston’s offense has thrown for 340 passing yards in 2 games (just 170.0 YPG) this season — 33rd-worst among FBS offenses. Colorado’s defense has allowed 227.5 passing yards per game this season — 3rd-worst among Big 12 defenses.

Houston Skill Players averaged a touchdown every 20.0 receptions (180 Rec/9 TDs) last season– worst Receptions Per TD among Big 12 Teams; Average: 11.0

Houston’s WRs has 120 receptions in 14 games (just 8.6 per game) since the 2024 season — 2nd-worst among Big 12 WRs. Colorado’s defense has allowed just 10.5 receptions per game to WRs since the 2024 season — T-26th-best among FBS defenses.

Houston has 211 receptions in 14 games (just 15.1 per game) since the 2024 season — T-21st-worst among FBS skill players. Colorado’s defense has allowed just 17.3 receptions per game since the 2024 season — 5th-best among Big 12 defenses.

Houston’s QBs has thrown for 340 passing yards in 2 games (just 170.0 YPG) this season — 33rd-worst among FBS teams. Colorado’s defense has allowed 227.5 passing yards per game this season — 3rd-worst among Big 12 defenses.

Colorado Defensive Stats & Trends

Colorado sacked opposing QBs on 10% of pass attempts (39/391) last season– best in the Big 12; Average: 6%

Colorado has allowed opponents to rush for 20+ yards on 3 of their 47 carries (6%) this season– worst in the Big 12; Average: 2%

Colorado has allowed 320.0 rushing yards per game (320/1) this season– worst among Power Conference Teams; Average: 109.3

Colorado has allowed 320.0 rushing yards per game (320/1) this season– worst in the Big 12; Average: 103.3

Colorado has allowed 6.8 Yards per Carry (320 yards/47 carries) this season– worst in the Big 12; Average: 3.1

Houston Defensive Stats & Trends

Houston has allowed first downs on 46% of pass attempts in the Red Zone since the 2024 season– worst among Power Conference Teams; Average: 22%

Houston has allowed passes of 20+ yards on just 1 of 55 attempts (2%) on 3rd and long since the 2024 season– best in the Big 12; Average: 10%

Houston allowed passes of 20+ yards on just 1 of 45 attempts (2%) on 3rd and long last season– best in the Big 12; Average: 11%

Houston allowed first downs on 46% of pass attempts in the Red Zone last season– worst among Power Conference Teams; Average: 22%

Houston has averaged 2.00 interceptions per game (2/1) this season– T-8th-best in FBS; Average: 0.71


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